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   Articles with "calcium dependent" as a keyword



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Deacylation of Calcium‐Dependent Antibiotics from Streptomyces violaceoruber in Co‐culture with Streptomyces sp. MG7‐G1

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recommendations! Published in 2020 at "Chembiochem"

DOI: 10.1002/cbic.202000404

Abstract: When Streptomyces violaceoruber grows together with Streptomyces sp. MG7‐G1, it reacts with strongly induced droplet production on its aerial mycelium. Initially the metabolite profile of droplets from S. violaceoruber in co‐culture with Streptomyces sp. MG7‐G1… read more here.

Keywords: dependent antibiotics; calcium dependent; streptomyces violaceoruber; culture ... See more keywords

The role of calcium-dependent protein kinase (CDPK) genes in plant stress resistance and secondary metabolism regulation

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recommendations! Published in 2025 at "Plant Growth Regulation"

DOI: 10.1007/s10725-025-01295-6

Abstract: Calcium signaling is known to play an important role in the activation of plant responses to abiotic and biotic stresses. Calcium-dependent protein kinases (CDPKs) are currently recognized as important calcium sensors in plants. This review… read more here.

Keywords: plant; plant stress; cdpk genes; calcium dependent ... See more keywords

Rapeseed calcium-dependent protein kinase CPK6L modulates reactive oxygen species and cell death through interacting and phosphorylating RBOHD.

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recommendations! Published in 2019 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2019.08.118

Abstract: Reactive oxygen species (ROS) play important roles in plant growth, development, responses to abiotic and biotic stresses. Hypersensitive response (HR)-like cell death is often associated with excess ROS. However, how a calcium-dependent protein kinase (CPK)… read more here.

Keywords: protein; reactive oxygen; death; calcium dependent ... See more keywords
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The calcium-dependent protease calpain in neuronal remodeling and neurodegeneration

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recommendations! Published in 2021 at "Trends in Neurosciences"

DOI: 10.1016/j.tins.2021.07.003

Abstract: Calpains are evolutionarily conserved and widely expressed Ca2+-activated cysteine proteases that act at neutral pH. The activity of calpains is tightly regulated, given that their abnormal activation can have deleterious effects leading to promiscuous cleavage… read more here.

Keywords: calcium dependent; calpain neuronal; neurodegeneration; protease calpain ... See more keywords

The calcium-dependent protein kinase 1 from Toxoplasma gondii as target for structure-based drug design

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recommendations! Published in 2017 at "Parasitology"

DOI: 10.1017/s0031182017001901

Abstract: Summary The apicomplexan protozoan parasites include the causative agents of animal and human diseases ranging from malaria (Plasmodium spp.) to toxoplasmosis (Toxoplasma gondii). The complex life cycle of T. gondii is regulated by a unique… read more here.

Keywords: calcium dependent; dependent protein; gondii; structure based ... See more keywords

Glycinocins E-H, Antimicrobial Lipopeptides Produced by a Streptomyces Strain.

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recommendations! Published in 2025 at "Journal of natural products"

DOI: 10.1021/acs.jnatprod.5c00740

Abstract: In an antifungal screening of extracts from microbial strains isolated from gypsum outcrops in Granada, Spain, four new cyclic lipopeptides, glycinocins E-H (1-4), were identified from Streptomyces sp. CA-297274 and exhibited potent activity against Zymoseptoria… read more here.

Keywords: glycinocins antimicrobial; antimicrobial lipopeptides; calcium dependent; produced streptomyces ... See more keywords

Antibacterial drugs: Discovering antibiotics through soil metagenomics

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recommendations! Published in 2018 at "Nature Reviews Drug Discovery"

DOI: 10.1038/nrd.2018.36

Abstract: products with antimicrobial properties has been hampered by the fact that many bacteria cannot be cultured in the laboratory, and those that can do not produce all of their natural products in this setting. Hover… read more here.

Keywords: calcium dependent; natural products; adenylation; calcium ... See more keywords

STAC proteins associate to the IQ domain of CaV1.2 and inhibit calcium-dependent inactivation

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recommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.1715997115

Abstract: Significance Association of the adaptor protein STAC3 to the calcium channel was recently identified as essential for skeletal muscle contraction. While STAC3 is expressed exclusively in skeletal muscle, the other two isoforms, STAC1 and STAC2,… read more here.

Keywords: stac proteins; calcium dependent; cav1; domain ... See more keywords
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In-silico analysis of Calcium Dependent Protein Kinase 6 of Cryptosporidium parvum through molecular modeling, docking, and dynamics simulation study

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recommendations! Published in 2020 at "Journal of Biomolecular Structure and Dynamics"

DOI: 10.1080/07391102.2020.1790036

Abstract: Abstract Calcium Dependent Protein Kinases are found in the Apicomplexan, algae, and plants; however, they are not reported in vertebrates and are regarded as excellent drug targets for pharmaceutical interventions. Calcium Dependent Protein Kinases of… read more here.

Keywords: dependent protein; calcium dependent; study; protein kinase ... See more keywords

Anthrax protective antigen is a calcium-dependent serine protease

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recommendations! Published in 2018 at "Virulence"

DOI: 10.1080/21505594.2018.1486139

Abstract: ABSTRACT Bacillus anthracis secretes a three component exotoxin-complex, which contributes to anthrax pathogenesis. Formation of this complex starts with the binding of protective antigen (PA) to its cellular receptor. In this study, we report that… read more here.

Keywords: calcium dependent; serine protease; protective antigen; dependent serine ... See more keywords

Calcium-dependent protein kinases 5 and 13 enhance salt tolerance in rice by directly activating OsMPK3/6 kinases

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recommendations! Published in 2024 at "Plant Physiology"

DOI: 10.1093/plphys/kiae520

Abstract: Abstract Mitogen-activated protein kinases (MAPKs/MPKs) are pivotal regulators in many stress-signaling pathways in plants. The dual phosphorylation of the TXY motif by MAP kinase kinases (MKKs) is essential for activating MAPKs. Here, we reveal a… read more here.

Keywords: protein kinases; tolerance; rice; salt ... See more keywords