A Calcium Imaging Approach to Measure Functional Sensitivity of Neurons.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1896-7_11
Abstract: Pain associated with chemotherapy and radiation therapy is one of the most common reasons for discontinuation of these treatments and has a dramatic effect on the quality of life in cancer patients. However, the mechanisms… read more here.
Keywords: measure functional; calcium imaging; pain; imaging approach ... See more keywords
Analysis of Feedback Signaling from Horizontal Cells to Photoreceptors in Mice.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7720-8_12
Abstract: Genetic manipulation of horizontal cells using a Connexin57-iCre mouse (Cx57-iCre) line combined with calcium imaging is proving to be a valuable method to study horizontal cell feedback inhibition onto photoreceptor terminals. While it is accepted… read more here.
Keywords: calcium imaging; feedback inhibition; feedback; horizontal cells ... See more keywords
High-Throughput Calcium Imaging Screen of Toxins' Function in Dissociated Sensory Neurons.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9845-6_15
Abstract: Many toxins from a variety of venomous animals and plants have evolved to target neuronal ion channels and receptors. However, a significant obstacle in the study of these toxins is the finding and characterization of… read more here.
Keywords: screen toxins; calcium imaging; throughput calcium; calcium ... See more keywords
Two-photon calcium imaging of seizures in awake, head-fixed mice.
Sign Up to like & getrecommendations! Published in 2021 at "Cell calcium"
DOI: 10.1016/j.ceca.2021.102380
Abstract: Epilepsy is a severe neurological disorder defined by spontaneous seizures. Current treatment options fail in a large proportion of patients, while questions as to the basic mechanisms of seizure initiation and propagation remain. Advances in… read more here.
Keywords: photon calcium; two photon; head fixed; calcium imaging ... See more keywords
Large-scale two-photon calcium imaging in freely moving mice
Sign Up to like & getrecommendations! Published in 2022 at "Cell"
DOI: 10.1016/j.cell.2022.02.017
Abstract: We developed a miniaturized two-photon microscope (MINI2P) for fast, high-resolution, multiplane calcium imaging of over 1,000 neurons at a time in freely moving mice. With a microscope weight below 3 g and a highly flexible connection… read more here.
Keywords: two photon; freely moving; moving mice; large scale ... See more keywords
MIN1PIPE: A Miniscope 1-Photon-Based Calcium Imaging Signal Extraction Pipeline.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.05.062
Abstract: In vivo calcium imaging using a 1-photon-based miniscope and a microendoscopic lens enables studies of neural activities in freely behaving animals. However, the high and fluctuating background, the inevitable movements and distortions of imaging field, and… read more here.
Keywords: photon; pipeline; miniscope photon; calcium imaging ... See more keywords
CALIMA: The semi-automated open-source calcium imaging analyzer
Sign Up to like & getrecommendations! Published in 2019 at "Computer Methods and Programs in Biomedicine"
DOI: 10.1016/j.cmpb.2019.104991
Abstract: Highlights • Although calcium imaging is widely used in biological research, there are relatively few tools available for its analysis. These tools often enable only part of the analysis or require expensive software packages to… read more here.
Keywords: semi automated; open source; calcium; calcium imaging ... See more keywords
Analysis pipelines for calcium imaging data
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Neurobiology"
DOI: 10.1016/j.conb.2018.11.004
Abstract: Calcium imaging is a popular tool among neuroscientists because of its capability to monitor in vivo large neural populations across weeks with single neuron and single spike resolution. Before any downstream analysis, the data needs… read more here.
Keywords: imaging data; data analysis; analysis; calcium imaging ... See more keywords
In vivo calcium imaging reveals disordered interictal network dynamics in epileptic stxbp1b zebrafish
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.102558
Abstract: Summary STXBP1 mutations are associated with encephalopathy, developmental delay, intellectual disability, and epilepsy. While neural networks are known to operate at a critical state in the healthy brain, network behavior during pathological epileptic states remains… read more here.
Keywords: calcium imaging; imaging reveals; vivo calcium; network ... See more keywords
NoRMCorre: An online algorithm for piecewise rigid motion correction of calcium imaging data
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroscience Methods"
DOI: 10.1016/j.jneumeth.2017.07.031
Abstract: BACKGROUND Motion correction is a challenging pre-processing problem that arises early in the analysis pipeline of calcium imaging data sequences. The motion artifacts in two-photon microscopy recordings can be non-rigid, arising from the finite time… read more here.
Keywords: motion; motion correction; calcium imaging; rigid motion ... See more keywords
Low computational-cost cell detection method for calcium imaging data
Sign Up to like & getrecommendations! Published in 2022 at "Neuroscience research"
DOI: 10.1016/j.neures.2022.02.008
Abstract: The rapid progress of calcium imaging techniques has reached a point where the activity of thousands to tens of thousands of cells can be recorded simultaneously with single-cell resolution in a field-of-view (FOV) of about… read more here.
Keywords: low computational; cell; cell detection; computational cost ... See more keywords