Intracellular Calcium Mobilization Is Required for Sonic Hedgehog Signaling.
Sign Up to like & getrecommendations! Published in 2018 at "Developmental cell"
DOI: 10.1016/j.devcel.2018.04.013
Abstract: Graded Shh signaling across fields of precursor cells coordinates patterns of gene expression, differentiation, and morphogenetic behavior as precursors form complex structures, such as the nervous system, the limbs, and craniofacial skeleton. Here we discover… read more here.
Keywords: mobilization required; intracellular calcium; calcium mobilization; shh dependent ... See more keywords
Mycobacterial Lipids Induce Calcium Mobilization and Degranulation of Mast Cells
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Respiratory and Critical Care Medicine"
DOI: 10.1164/rccm.201803-0436le
Abstract: J Med 2018;378:829–839. 3. Palevsky PM, Molitoris BA, Okusa MD, Levin A, Waikar SS, Wald R, et al. Design of clinical trials in acute kidney injury: report from an NIDDK workshop on trial methodology. Clin… read more here.
Keywords: mycobacterial lipids; medicine; induce calcium; mobilization degranulation ... See more keywords
Development and validation of a high-throughput calcium mobilization assay for the orphan receptor GPR88
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biomedical Science"
DOI: 10.1186/s12929-017-0330-3
Abstract: BackgroundGPR88 is an orphan G protein-coupled receptor highly expressed in the striatum and is implicated in basal ganglia-associated disorders. However, the receptor functions of GPR88 are still largely unknown due to the lack of potent… read more here.
Keywords: gpr88; calcium mobilization; mobilization assay; calcium ... See more keywords
Development of a High-Throughput Calcium Mobilization Assay for CCR6 Receptor Coupled to Hydrolase Activity Readout
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10020422
Abstract: CCR6 is a chemokine receptor highly implicated in inflammatory diseases and could be a potential therapeutic target; however, no therapeutic agents targeting CCR6 have progressed into clinical evaluation. Development of a high-throughput screening assay for… read more here.
Keywords: ccr6; calcium mobilization; high throughput;