Cu–Ferrocene‐Functionalized CaO2 Nanoparticles to Enable Tumor‐Specific Synergistic Therapy with GSH Depletion and Calcium Overload
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Science"
DOI: 10.1002/advs.202100241
Abstract: Abstract The conversion of endogenous H2O2 into toxic hydroxyl radical (•OH) via catalytic nanoparticles is explored for tumor therapy and received considerable success. The intrinsic characteristics of microenvironment in tumor cells, such as limited H2O2… read more here.
Keywords: ferrocene; cao2 nanoparticles; calcium overload; therapy ... See more keywords
Capsaicin-Decorated Semiconducting Polymer Nanoparticles for Light-Controlled Calcium-Overload/Photodynamic Combination Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202200152
Abstract: Calcium-overload cancer therapy has gained more and more attention owing to its good therapeutic efficacy with low side effect. However, conventional calcium-overload therapy is achieved by introducing an additional calcium element into the tumor site… read more here.
Keywords: calcium; calcium overload; semiconducting polymer; therapy ... See more keywords
Research Progress on the Relationship Between Acute Pancreatitis and Calcium Overload in Acinar Cells
Sign Up to like & getrecommendations! Published in 2018 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-018-5297-8
Abstract: Acute pancreatitis is a human disease with multiple causes that leads to autodigestion of the pancreas. There is sufficient evidence to support the key role of sustained increase in cytosolic calcium concentrations in the early… read more here.
Keywords: acute pancreatitis; overload acinar; calcium overload; acinar cells ... See more keywords
LPS-induced vein endothelial cell injury and acute lung injury have Btk and Orai 1 to regulate SOC-mediated calcium influx.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.107039
Abstract: Patients with sepsis and sepsis-related complications have a high mortality. Endothelial cell dysfunction plays a central role in sepsis pathophysiological process. In sepsis patients, endothelial cell apoptosis is associated with intracellular calcium overload. Multiple functions… read more here.
Keywords: lps induced; endothelial cell; calcium overload; calcium ... See more keywords
Impact of calcium overload on bone and mineral metabolism at 55 hemodialysis centers in Lima
Sign Up to like & getrecommendations! Published in 2018 at "Nefrologia"
DOI: 10.1016/j.nefroe.2018.03.008
Abstract: Abstract Background Mineral and bone metabolism disorders are common complications in hemodialysis patients that present significant geographical variability. Objectives The objective of this study was to assess these disorders for the first time in hemodialysis… read more here.
Keywords: hemodialysis; metabolism; bone; calcium overload ... See more keywords
Hydroxysafflor Yellow A Ameliorates Myocardial Ischemia/Reperfusion Injury by Suppressing Calcium Overload and Apoptosis
Sign Up to like & getrecommendations! Published in 2021 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2021/6643615
Abstract: Myocardial ischemia/reperfusion injury (MI/RI) is an urgent problem with a great impact on health globally. However, its pathological mechanisms have not been fully elucidated. Hydroxysafflor yellow A (HSYA) has a protective effect against MI/RI. This… read more here.
Keywords: hsya; apoptosis; effect; calcium overload ... See more keywords
Abstract 882: The Valosin-containing Protein Resists Pathological Cardiac Calcium Overload via Inhibiting Mitochondrial Calcium Uptake
Sign Up to like & getrecommendations! Published in 2019 at "Circulation Research"
DOI: 10.1161/res.125.suppl_1.882
Abstract: Stress-induced mitochondrial calcium (Ca 2+ ) overload is a trigger of cardiomyocyte death though the opening of mitochondrial permeability transition pore (mPTP) during cardiac ischemic injury. We previously found that the valosin-containing protein (VCP), an… read more here.
Keywords: protein; mitochondrial calcium; calcium overload; calcium ... See more keywords