Inhibitors of Calcium Oxalate Crystallization for the Treatment of Oxalate Nephropathies
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DOI: 10.1002/advs.201903337
Abstract: Abstract Calcium oxalate (CaOx) crystal‐induced nephropathies comprise a range of kidney disorders, for which there are no efficient pharmacological treatments. Although CaOx crystallization inhibitors have been suggested as a therapeutic modality already decades ago, limited… read more here.
Keywords: caox; treatment; crystallization; calcium oxalate ... See more keywords
Renal Calcium Oxalate Deposits Induce a Pro‐Atherosclerotic and Pro‐Osteoporotic Response in Mice
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.25924
Abstract: Urinary stone disease (USD) is increasing in adult and pediatric populations. Adult and pediatric studies have demonstrated decreased bone mineral density and increased fracture rates. USD has also been independently linked to increased rates of… read more here.
Keywords: array showed; upregulation genes; mice; calcium oxalate ... See more keywords
Protein Network Analysis and Functional Studies of Calcium Oxalate Crystal‐Induced Cytotoxicity in Renal Tubular Epithelial Cells
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DOI: 10.1002/pmic.201800008
Abstract: Our previous expression study has reported a set of proteins with altered levels in renal tubular cells after exposure to calcium oxalate monohydrate (COM) crystals, which are the main composition of kidney stones. However, their… read more here.
Keywords: protein network; analysis; renal tubular; calcium oxalate ... See more keywords
Analyses of long non-coding RNA and mRNA profiling using RNA sequencing in calcium oxalate monohydrate-stimulated renal tubular epithelial cells
Sign Up to like & getrecommendations! Published in 2018 at "Urolithiasis"
DOI: 10.1007/s00240-018-1065-7
Abstract: To study the expression profiles of lncRNA and mRNA in the calcium oxalate monohydrate-attached HK-2 cells, and investigate the association between critical lncRNA expression level and renal injury. The HK-2 cells were treated with crystal… read more here.
Keywords: rna; oxalate monohydrate; oxalate crystals; calcium oxalate ... See more keywords
Selective protein enrichment in calcium oxalate stone matrix: a window to pathogenesis?
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DOI: 10.1007/s00240-019-01131-3
Abstract: Urine proteins are thought to control calcium oxalate stone formation, but over 1000 proteins have been reported in stone matrix obscuring their relative importance. Proteins critical to stone formation should be present at increased relative… read more here.
Keywords: stone; matrix; stone matrix; calcium oxalate ... See more keywords
Impact of age and renal function on urine chemistry in patients with calcium oxalate kidney stones
Sign Up to like & getrecommendations! Published in 2021 at "Urolithiasis"
DOI: 10.1007/s00240-021-01254-6
Abstract: Nephrolithiasis is associated with an increased risk of chronic kidney disease, and its incidence varies with age. However, little is known on the combined impact of aging and declining renal function on urinary risk factors… read more here.
Keywords: age; chemistry; creatinine clearance; calcium oxalate ... See more keywords
Comparative functional analysis of the urinary tract microbiome for individuals with or without calcium oxalate calculi
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DOI: 10.1007/s00240-022-01314-5
Abstract: Individuals with urinary stone disease (USD) exhibit dysbiosis in the urinary tract and the loss of Lactobacillus that promote urinary tract health. However, the microbial metabolic functions that differentiate individuals with USD from healthy individuals… read more here.
Keywords: stone; calcium oxalate; tract; urinary tract ... See more keywords
The Occurrence of Calcium Oxalate Crystals and Distribution of Arabinogalactan Proteins (AGPs) in Ovary Cells During Fragaria x ananassa (Duch.) Development
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Plant Growth Regulation"
DOI: 10.1007/s00344-018-09912-7
Abstract: In this study, the presence of calcium oxalate crystals and distribution of arabinogalactan proteins (AGPs) in the ovary of Fragaria x ananassa (Duchesne) were investigated. The arrangement of the AGP epitopes was analyzed using immunohistochemistry… read more here.
Keywords: oxalate crystals; crystals distribution; calcium oxalate; distribution arabinogalactan ... See more keywords
Hydroxyproline and starch consumption and urinary supersaturation with calcium oxalate in cats
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DOI: 10.1016/j.anifeedsci.2018.10.001
Abstract: Abstract The effect of extruded foods intake with different contents of starch, protein and hydroxyproline were evaluated on water balance, oxalate renal excretion, urine chemical composition and the relative urine supersaturation with calcium oxalate (RSSCaOx)… read more here.
Keywords: hydroxyproline starch; supersaturation calcium; hydroxyproline; calcium oxalate ... See more keywords
Artificially induced calcium oxalate on limestone in urban environments – New findings
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DOI: 10.1016/j.culher.2019.06.011
Abstract: Abstract Calcium oxalate, known for its greater resistance to deterioration when compared to calcium carbonate, is the desired end product when ammonium oxalate treatment is applied to calcareous stone. Calcium oxalate can form naturally, on… read more here.
Keywords: calcium oxalate; treatment; limestone; salt ... See more keywords
Flavonoid-rich fraction from Pleroma pereirae (Melastomataceae): Effects on calcium oxalate crystallization, antioxidant and antinociceptive activities
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Integrative Medicine"
DOI: 10.1016/j.eujim.2020.101095
Abstract: Abstract Introduction Pleroma pereirae is a Brazilian endemic shrub used in the folk medicine for the treatment of kidney diseases. The aim of this study was the evaluation of the biological effects of the flavonoid-rich… read more here.
Keywords: medicine; pereirae; flavonoid rich; calcium oxalate ... See more keywords