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Published in 2017 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2017.04.316
Abstract: Loss-of-function mutations in PYCR2 cause hypomyelinating leukodystrophy 10 (HLD10) (MIM: 616420) characterized by postnatal degenerative microcephaly, severely delayed psychomotor development, and hypomyelination. Here, we report 3 additional patients with a novel germline homozygous missense G249V,…
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Keywords:
mouse brain;
spontaneous calcium;
waves developing;
brain ... See more keywords
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Published in 2017 at "Stem Cell Reports"
DOI: 10.1016/j.stemcr.2017.01.009
Abstract: Summary Brain injuries, such as stroke or trauma, induce neural stem cells in the subventricular zone (SVZ) to a neurogenic response. Very little is known about the molecular cues that signal tissue damage, even over…
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Keywords:
brain;
calcium;
injury;
calcium waves ... See more keywords
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Published in 2017 at "Developmental biology"
DOI: 10.1016/j.ydbio.2017.05.018
Abstract: The enteric nervous system (ENS) is an extensive network of neurons in the gut wall that arises from neural crest-derived cells. Like other populations of neural crest cells, it is known that enteric neural crest-derived…
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Keywords:
nervous system;
enccs;
enteric nervous;
calcium ... See more keywords
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Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abo6693
Abstract: In plants, a variety of stimuli trigger long-range calcium signals that travel rapidly along the vasculature to distal tissues via poorly understood mechanisms. Here, we use quantitative imaging and analysis to demonstrate that traveling calcium…
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Keywords:
bulk flow;
calcium;
diffusion bulk;
calcium waves ... See more keywords
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Published in 2025 at "PLOS Biology"
DOI: 10.1371/journal.pbio.3003181
Abstract: Successful initiation of animal development requires activation of the egg immediately prior to fusion of gamete pronuclei. In all taxa, this is initiated by waves of calcium transients which transverse across the egg. Calcium waves…
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Keywords:
protease;
egg activation;
activation;
egg ... See more keywords
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Published in 2025 at "Cancers"
DOI: 10.3390/cancers17111851
Abstract: Simple Summary Intercellular calcium waves (ICWs) are a class of molecular signals for long-range intercellular communication, influencing many key biological activities. Despite increasing evidence that mechanical signals across molecular to tissue scales initiate and modulate…
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Keywords:
intercellular calcium;
modulation physiological;
physiological roles;
mechanical modulation ... See more keywords