Adrenomedullin-CALCRL axis controls relapse-initiating drug tolerant acute myeloid leukemia cells
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-020-20717-9
Abstract: Drug tolerant/resistant leukemic stem cell (LSC) subpopulations may explain frequent relapses in acute myeloid leukemia (AML), suggesting that these relapse-initiating cells (RICs) persistent after chemotherapy represent bona fide targets to prevent drug resistance and relapse.… read more here.
Keywords: myeloid leukemia; calcrl; drug; drug tolerant ... See more keywords
42 Adrenomedullin Stimulates Proliferation, Migration and Adhesion of Porcine Trophectoderm Cells Via CALCRL-AKT-TSC2-MTORC1 Cell Signaling Pathway
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Animal Science"
DOI: 10.1093/jas/skad068.040
Abstract: Adrenomedullin (ADM) as a highly conserved peptide hormone has been reported to increase significantly in the uterine lumen during the peri-implantation period of pregnancy in pigs, but its functional roles in growth and development of… read more here.
Keywords: adhesion; cell; akt tsc2; calcrl ... See more keywords