Decrypting the interaction pattern of Piperlongumine with calf thymus DNA and dodecamer d(CGCGAATTCGCG)2 B-DNA: Biophysical and molecular docking analysis.
Sign Up to like & getrecommendations! Published in 2022 at "Biophysical chemistry"
DOI: 10.1016/j.bpc.2022.106808
Abstract: The mechanisms of interaction of DNA with pharmacological molecules are critical to understanding their therapeutic actions on physiological systems. Piperlongumine is widely studied for its anticancer potential. Multi-spectrometry, calorimetry and in silico studies were employed… read more here.
Keywords: dna; piperlongumine; calf thymus; interaction ... See more keywords
Exploring the binding of carbon dots to calf thymus DNA: From green synthesis to fluorescent molecular probe
Sign Up to like & getrecommendations! Published in 2018 at "Carbon"
DOI: 10.1016/j.carbon.2018.01.009
Abstract: Abstract Carbon dots (CDs) have been widely applied in bioimaging, drug delivery and nanomedicine. In this study, the interaction binding mechanism of CDs with calf thymus DNA (ctDNA) has been investigated. A bottom-up synthetic route… read more here.
Keywords: carbon; thymus dna; green synthesis; carbon dots ... See more keywords
Change of benzo(a)pyrene during frying and its groove binding to calf thymus DNA.
Sign Up to like & getrecommendations! Published in 2021 at "Food chemistry"
DOI: 10.1016/j.foodchem.2021.129276
Abstract: Benzo[a]pyrene (BaP), a prototype of polycyclic aromatic hydrocarbons (PAHs) with potential mutagenicity, toxicity and carcinogenicity, is ubiquitous in deep-fried foods. Herein, the changes in eight specific PAHs (PAH8) concentration in sunflower oil during frying were… read more here.
Keywords: groove binding; thymus dna; dna; benzo pyrene ... See more keywords
Binding interaction of spherical silver nanoparticles and calf thymus DNA: Comprehensive multispectroscopic, molecular docking, and RAPD PCR studies
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2019.111185
Abstract: Abstract It is well established that silver nanoparticles (AgNPs) can interact with deoxyribonucleic acid (DNA), inducing different DNA damages. Here, absorption spectra, fluorescence and synchronous fluorescence spectra, analysis of melting temperature curves, transmission electron microscopy… read more here.
Keywords: dna; molecular docking; interaction; silver nanoparticles ... See more keywords
Inclusion complex of β-cyclodextrin with tetrabutylammonium bromide: Synthesis, characterization and interaction with calf thymus DNA
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2019.111525
Abstract: Abstract Surfactant molecules are now become indispensible in drug formulations to reduce drug-drug interactions and most often to enhance the bioavailability of poorly water soluble life saving drugs. Recently, tetrabutylammonium bromide (TBAB) is the cationic… read more here.
Keywords: thymus dna; tetrabutylammonium bromide; inclusion; calf thymus ... See more keywords
A novel insight into the cytotoxic effects of Tephrosin with calf thymus DNA: Experimental and in silico approaches
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2020.114728
Abstract: Abstract Tephrosin (TP) is a retinoid isoflavonoid that possesses various pharmacological and biological properties such as antitumor activity, anti-inflammatory, antimicrobial, anthelmintic, and anti-insect effects. In this work, the DNA binding characteristics of Tephrosin (TP) and… read more here.
Keywords: novel insight; calf thymus; thymus dna; dna ... See more keywords
Insights into the binding properties of calf thymus DNA with lopinavir from spectroscopic and computational studies
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2021.115491
Abstract: Abstract Lopinavir (LPV), an important antiviral drug, can inhibit effectively wild type and mutant HIV protease. In this work, molecular interaction mechanism between LPV and calf thymus deoxyribonucleic acid (ct-DNA) was characterized by spectroscopic, viscosity… read more here.
Keywords: lopinavir; dna; lpv dna; insights binding ... See more keywords
Dual-Emissive Tris-Heteroleptic Ruthenium Complexes: Tuning the DNA-Triggered Ratiometric Emission Response by Ancillary Ligands.
Sign Up to like & getrecommendations! Published in 2021 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.1c02077
Abstract: Three tris-heteroleptic mononuclear Ru(II) complexes with dual fluorescence and phosphorescence-[Ru(dpma)(bpy)(phen)]2+ (12+), [Ru(dpma)(bpy)(dppz)]2+ (22+), and [Ru(dpma)(phen)(dppz)]2+ (32+)-have been designed and used as ratiometric light-response probes for DNA, where dpma is di(pyrid-2-yl)(methyl)-amine, bpy is 2,2'-bipyridine, phen is… read more here.
Keywords: tris heteroleptic; thymus dna; dna; bpy ... See more keywords
Elucidating the interaction of sulindac with calf thymus DNA: biophysical and in silico molecular modelling approach
Sign Up to like & getrecommendations! Published in 2017 at "New Journal of Chemistry"
DOI: 10.1039/c7nj03698a
Abstract: Sulindac is one of the most effective non-steroidal anti-inflammatory drugs (NSAIDs) and belongs to the arylalkanoic acid class. DNA is the major target for a wide range of therapeutic small molecules. Thus, deciphering the interaction… read more here.
Keywords: thymus dna; dna; silico molecular; molecular modelling ... See more keywords
Groove binding between ferulic acid and calf thymus DNA: spectroscopic methodology combined with chemometrics and molecular docking studies
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2019.1624194
Abstract: Abstract Ferulic acid (FA), a dietary phenolic acid compound, is proved to possess numerous biological activities. Hence, this study was devoted to explore the interaction between FA and calf thymus DNA (ctDNA) by UV − vis absorption,… read more here.
Keywords: methodology; ctdna; thymus dna; ferulic acid ... See more keywords
Elucidating the interaction of aminophylline with calf thymus DNA using multispectroscopic and molecular docking approach
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2020.1722240
Abstract: Abstract Aminophylline (Am) is a methylxanthine compound clinically applied for chronic lung diseases like asthma, bronchitis or emphysema. Chemically, it comprises theophylline and ethylenediamine in a ratio 2:1. For the widening of the therapeutic window… read more here.
Keywords: dna; thymus dna; aminophylline; approach ... See more keywords