Screening and Molecular Docking of Bioactive Metabolites of the Red Sea Sponge Callyspongia siphonella as Potential Antimicrobial Agents
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DOI: 10.3390/antibiotics11121682
Abstract: Marine sponges create a wide range of bioactive secondary metabolites, as documented throughout the year. Several bioactive secondary metabolites were isolated from different members of Callyspongia siphonella species. This study aimed for isolation and structural… read more here.
Keywords: molecular docking; callyspongia siphonella; activity; bioactive metabolites ... See more keywords
Bioactive Brominated Oxindole Alkaloids from the Red Sea Sponge Callyspongia siphonella
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DOI: 10.3390/md17080465
Abstract: In the present study, LC-HRESIMS-assisted dereplication along with bioactivity-guided isolation led to targeting two brominated oxindole alkaloids (compounds 1 and 2) which probably play a key role in the previously reported antibacterial, antibiofilm, and cytotoxicity… read more here.
Keywords: oxindole alkaloids; bioactive brominated; brominated oxindole; alkaloids red ... See more keywords