Calnexin/Calreticulin and Assays Related to N-Glycoprotein Folding In Vitro.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0430-4_29
Abstract: Calnexin (CNX) and calreticulin (CRT) are ER-resident lectin-like molecular chaperones involved in the quality control of secretory or membrane glycoproteins. They can exert molecular chaperone functions via specific binding to the early processing intermediates of… read more here.
Keywords: calnexin calreticulin; calnexin; calreticulin; cnx crt ... See more keywords
Role for N-glycans and calnexin-calreticulin chaperones in SARS-CoV-2 Spike maturation and viral infectivity
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abq8678
Abstract: Functional and epidemiological data suggest that N-linked glycans on the SARS-CoV-2 Spike protein may contribute to viral infectivity. To investigate this, we created a panel of N-to-Q mutations at N-glycosylation sites proximal to the Spike… read more here.
Keywords: calnexin calreticulin; cov spike; viral infectivity; calreticulin chaperones ... See more keywords