Cell-Permeable Calpain Inhibitor SJA6017 Provides Functional Protection to Spinal Motoneurons Exposed to MPP+
Sign Up to like & getrecommendations! Published in 2020 at "Neurotoxicity Research"
DOI: 10.1007/s12640-020-00264-3
Abstract: Extra-nigral central nervous system sites have been found to be affected in Parkinson’s disease (PD). In addition to substantia nigra, degeneration of spinal cord motor neurons may play a role in the motor symptoms of… read more here.
Keywords: mpp; calpain inhibitor; calpain; spinal motoneurons ... See more keywords
In vitro selection of Phytomonas serpens cells resistant to the calpain inhibitor MDL28170: alterations in fitness and expression of the major peptidases and efflux pumps
Sign Up to like & getrecommendations! Published in 2017 at "Parasitology"
DOI: 10.1017/s0031182017001561
Abstract: SUMMARY The species Phytomonas serpens is known to express some molecules displaying similarity to those described in trypanosomatids pathogenic to humans, such as peptidases from Trypanosoma cruzi (cruzipain) and Leishmania spp. (gp63). In this work,… read more here.
Keywords: calpain inhibitor; calpain; resistant calpain; expression ... See more keywords
Calpain-2 as a Treatment Target in Prenatal Stress-induced Epileptic Spasms in Infant Rats
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Neurobiology"
DOI: 10.5607/en.2019.28.4.529
Abstract: Stress can induce a serious epileptic encephalopathy that occurs during early infancy. Recent studies have revealed that prenatal stress exposure is a risk factor for the development of infantile spasms. Our previous work demonstrates that… read more here.
Keywords: calpain inhibitor; prenatal stress; epileptic spasms; treatment ... See more keywords