Biological therapy downregulates the heterodimer S100A8/A9 (calprotectin) expression in psoriatic patients
Sign Up to like & getrecommendations! Published in 2018 at "Inflammation Research"
DOI: 10.1007/s00011-018-1147-6
Abstract: The pathophysiology of psoriasis is very complex and involves an interplay between immune cells and keratinocytes. The keratinocyte production of calprotectin (S100A8/A9), induced by the inflammatory psoriatic milieu, may be involved in initiating immune cell… read more here.
Keywords: biological therapy; psoriatic patients; s100a8; expression ... See more keywords
Circulating calprotectin as a supporting inflammatory marker in discriminating SARS-CoV-2 infection: an observational study
Sign Up to like & getrecommendations! Published in 2021 at "Inflammation Research"
DOI: 10.1007/s00011-021-01465-y
Abstract: Objective and design Fecal calprotectin (CLP) is widely known for its detection in stools of patients with inflammatory bowel diseases (IBDs), to investigate the intestinal inflammatory status. Current research is promoting the circulating protein role… read more here.
Keywords: infection; calprotectin; sars cov; circulating calprotectin ... See more keywords
Synovial fluid calprotectin in diagnosing periprosthetic joint infection: A meta-analysis
Sign Up to like & getrecommendations! Published in 2022 at "International Orthopaedics"
DOI: 10.1007/s00264-022-05357-6
Abstract: Periprosthetic joint infection (PJI) is one of the most debilitating complications following joint replacement surgery. Synovial biomarkers, such as Calprotectin, have become valuable in the diagnosis of PJI. This meta-analysis aimed to investigate the role… read more here.
Keywords: joint infection; periprosthetic joint; calprotectin; meta analysis ... See more keywords
Circulating calprotectin as a biomarker of laryngeal carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-017-4480-4
Abstract: Calprotectin is an S100 protein and marker of inflammation found in neutrophils and monocytes; S100 proteins are a family of calcium-modulated proteins. The aim of this study was to determine if the serum concentration of… read more here.
Keywords: serum calprotectin; pathology; laryngeal carcinoma; calprotectin concentration ... See more keywords
Urinary calprotectin, kidney injury molecule-1, and neutrophil gelatinase-associated lipocalin for the prediction of adverse outcome in pediatric acute kidney injury
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pediatrics"
DOI: 10.1007/s00431-017-2907-y
Abstract: AbstractEarly identification of patients with acute kidney injury (AKI) being at high risk for adverse outcome can influence medical treatment. This study compares urinary calprotectin, kidney injury molecule-1 (KIM-1), and neutrophil gelatinase-associated lipocalin (NGAL) for… read more here.
Keywords: kidney injury; calprotectin; performance; injury ... See more keywords
Salivary calprotectin is elevated in patients with active inflammatory bowel disease.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2019.104528
Abstract: OBJECTIVES To assess the concentration of calprotectin, a heterodimer of S100A8 and S100A9 implicated in inflammatory bowel disease (IBD), in saliva of IBD patients compared to controls. METHODS Unstimulated and stimulated saliva, and serum was… read more here.
Keywords: bowel disease; saliva; inflammatory bowel; stimulated saliva ... See more keywords
Biological variation of serum canine calprotectin concentrations as measured by ELISA in healthy dogs.
Sign Up to like & getrecommendations! Published in 2019 at "Veterinary journal"
DOI: 10.1016/j.tvjl.2019.03.002
Abstract: Calprotectin is a useful biomarker of inflammation in dogs. However, the biological variation of serum canine calprotectin is unknown. Indices of biological variation were determined in serial serum samples (n=147) from 11 healthy dogs (males/females:… read more here.
Keywords: serum; serum canine; calprotectin; biological variation ... See more keywords
Nickel Sequestration by the Host-Defense Protein Human Calprotectin.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b01212
Abstract: The human innate immune protein calprotectin (CP, S100A8/S100A9 oligomer, calgranulin A/calgranulin B oligomer, MRP-8/MRP-14 oligomer) chelates a number of first-row transition metals, including Mn(II), Fe(II), and Zn(II), and can withhold these essential nutrients from microbes.… read more here.
Keywords: protein; sequestration host; chemistry; nickel sequestration ... See more keywords
Biochemical and Spectroscopic Observation of Mn(II) Sequestration from Bacterial Mn(II) Transport Machinery by Calprotectin.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b11207
Abstract: Human calprotectin (CP, S100A8/S100A9 oligomer) is a metal-sequestering host-defense protein that prevents bacterial acquisition of Mn(II). In this work, we investigate Mn(II) competition between CP and two solute-binding proteins that Staphylococcus aureus and Streptococcus pneumoniae,… read more here.
Keywords: observation sequestration; sequestration bacterial; spectroscopic; calprotectin ... See more keywords
Plasma calprotectin in the emergency department: a potential clinical biomarker for patients with infectious diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Scandinavian journal of clinical and laboratory investigation"
DOI: 10.1080/00365513.2021.1980223
Abstract: Increased levels of plasma calprotectin are reported in patients with infectious diseases. However, the clinical usefulness of calprotectin as a biomarker to identify patients with infectious diseases in the emergency department (ED) setting has not… read more here.
Keywords: plasma calprotectin; infectious diseases; patients infectious; emergency department ... See more keywords
Fecal calprotectin as a biomarker of intestinal inflammation in ICU patients with diarrhea – testing the pipette method against the collection pin and weighing methods
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2022.2107567
Abstract: Abstract Fecal calprotectin is an established biomarker in inflammatory bowel disease, but its role in assessment of intestinal inflammation in ICU patients is yet to be explored. ICU patients tend to acquire diarrhea, which complicates… read more here.
Keywords: pipette method; calprotectin; icu patients; method ... See more keywords