RAPID LOW-COST DETECTION OF TYPE 2CALR MUTATION BY ALLELE-SPECIFIC RT-PCR FOR DIAGNOSIS OF MYELOPROLIFERATIVE NEOPLASMS.
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DOI: 10.32471/exp-oncology.2312-8852.vol-44-no-1.17329
Abstract: BACKGROUND Approximately 15% to 24% of essential thrombocythemia (ET) and 25-35% of primary myelofibrosis cases carry a mutation in the calreticulin (CALR) gene. Sanger sequencing, qPCR, high resolution melt or targeted next generation sequencing usually… read more here.
Keywords: calr gene; allele specific; low cost; mutation ... See more keywords