Most bicarbonate secretion by Calu‐3 cells is mediated by CFTR and independent of pendrin
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DOI: 10.14814/phy2.13641
Abstract: Bicarbonate plays an important role in airway host defense, however, its transport mechanisms remain uncertain. Here we examined the relative contributions of the anion channel CFTR (cystic fibrosis transmembrane conductance regulator, ABCC7) and the anion… read more here.
Keywords: calu cells; secretion calu; calu; hco3 ... See more keywords
Cell Derived Matrix Fibulin-1 Associates With Epidermal Growth Factor Receptor to Inhibit Its Activation, Localization and Function in Lung Cancer Calu-1 Cells
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DOI: 10.3389/fcell.2020.00522
Abstract: Epidermal Growth Factor Receptor (EGFR) is a known promoter of tumor progression and is overexpressed in lung cancers. Growth factor receptors (including EGFR) are known to interact with extracellular matrix (ECM) proteins, which regulate their… read more here.
Keywords: growth factor; calu cells; activation; lung ... See more keywords
Oxidative Stress, Cytotoxic and Inflammatory Effects of Urban Ultrafine Road-Deposited Dust from the UK and Mexico in Human Epithelial Lung (Calu-3) Cells
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DOI: 10.3390/antiox11091814
Abstract: Road-deposited dust (RD) is a pervasive form of particulate pollution identified (typically via epidemiological or mathematical modelling) as hazardous to human health. Finer RD particle sizes, the most abundant (by number, not mass), may pose… read more here.
Keywords: road; deposited dust; road deposited; cytotoxic ... See more keywords
The Bioactive Phenolic Agents Diaryl Ether CVB2-61 and Diarylheptanoid CVB4-57 as Connexin Hemichannel Blockers
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DOI: 10.3390/ph15101173
Abstract: Inflammation mediators enhance the activity of connexin (Cx) hemichannels, especially in the epithelial and endothelial tissues. As potential release routes for injury signals, such as (oligo)nucleotides, Cx hemichannels may contribute to long-lasting inflammation. Specific inhibition… read more here.
Keywords: phenolic agents; bioactive phenolic; cvb4; calu cells ... See more keywords