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The Molecular Simulation Study of nNOS Activation Induced by the Interaction Between Its Calmodulin-Binding Domain and SUMO1

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Published in 2020 at "Frontiers in Molecular Neuroscience"

DOI: 10.3389/fnmol.2020.535494

Abstract: Neuronal nitric oxide synthase (nNOS), an enzyme required for learning and memory, catalyzes L-arginine decomposition during nitric oxide production in mammalian neurons. Over-activation of nNOS leads to oxidative/nitrosative stress, which is part of the pathophysiological… read more here.

Keywords: binding domain; sumo1; study; activation ... See more keywords