Imperatorin ameliorates learning and memory deficits through BDNF/TrkB and ERK/CaMKIIα/CREB signaling in prenatally‐stressed female offspring
Sign Up to like & getrecommendations! Published in 2020 at "Phytotherapy Research"
DOI: 10.1002/ptr.6692
Abstract: Prenatal stress (PS) can lead to impaired spatial learning and memory in offspring. Imperatorin (IMP) is a naturally occurring furanocoumarin with many pharmacological properties. However, the effects of IMP on cognitive impairment induced by PS… read more here.
Keywords: learning memory; camkii creb; bdnf trkb; memory deficits ... See more keywords
The κ-Opioid Receptor Agonist U50488H Ameliorates Neuropathic Pain Through the Ca2+/CaMKII/CREB Pathway in Rats
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DOI: 10.2147/jir.s327234
Abstract: Objective To observe the ameliorative effect of kappa opioid receptor (KOR) agonist on rats with neuropathic pain (NP) and investigate the mechanism of action of the calcium ion (Ca2+)/calcium/calmodulin-dependent protein kinase II (CaMKII)/cyclic AMP response… read more here.
Keywords: camkii creb; creb pathway; group; agonist u50488h ... See more keywords
Effects of intrathecal bupivacaine on the NR2B/CaMKIIα/CREB signaling pathway in the rat lumbar spinal cord
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DOI: 10.3892/mmr.2018.8448
Abstract: Neuraxial anesthesia produces an anesthetic-sparing, sedative effect. The mechanism underlying this effect potentially involves decreased spinal afferent input. However, the neurochemical mechanisms at the spinal level remain unknown. The N-methyl-D-aspartate receptor 2B subunit/calcium-calmodulin-dependent protein kinase… read more here.
Keywords: nr2b camkii; creb signaling; bupivacaine; camkii ... See more keywords