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Heterosynaptic long-term potentiation of non-nociceptive synapses requires endocannabinoids, NMDARs, CamKII, and PKCζ.

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1 Published in 2023 at "Journal of neurophysiology"

DOI: 10.1152/jn.00494.2022

Abstract: Noxious stimuli or injury can trigger long-lasting sensitization to non-nociceptive stimuli (referred to as allodynia in mammals). Long-term potentiation (LTP) of nociceptive synapses has been shown to contribute to nociceptive sensitization (hyperalgesia) and there is… read more here.

Keywords: long term; non nociceptive; camkii pkc; term potentiation ... See more keywords