Conformation-Dependent Reversible Interaction of Ca2+/Calmodulin-Dependent Protein Kinase Kinase with an Inhibitor, TIM-063.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemistry"
DOI: 10.1021/acs.biochem.1c00796
Abstract: Ca2+/calmodulin-dependent protein kinase kinase (CaMKK), a Ca2+/CaM-dependent enzyme that phosphorylates and activates multifunctional kinases, including CaMKI, CaMKIV, protein kinase B/Akt, and 5'AMP-activated protein kinase, is involved in various Ca2+-signaling pathways in cells. Recently, we developed… read more here.
Keywords: tim 063; kinase; 127 sepharose; tim 127 ... See more keywords
Intracellular Calcium Overload and Activation of CaMKK/AMPK Signaling Are Related to the Acceleration of Muscle Glycolysis of Broiler Chickens Subjected to Acute Stress.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c07391
Abstract: The current study investigated the effect of preslaughter transport on stress response and meat quality of broilers and explored the underlying mechanisms involved in the regulation of muscle glycolysis through calcium/calmodulin-dependent protein kinase kinase (CaMKK)/AMP-activated… read more here.
Keywords: stress; calcium; muscle glycolysis; camkk ... See more keywords
Abstract WP254: Inhibition of Calcium/Calmodulin-Dependent Protein Kinase Kinase (CaMKK) Exacerbates Endothelial Cell Impairment After Cerebral Ischemia
Sign Up to like & getrecommendations! Published in 2018 at "Stroke"
DOI: 10.1161/str.49.suppl_1.wp254
Abstract: CaMKK (α and β) is a major kinase activated by elevated intracellular calcium. We have previously demonstrated CaMKK is neuroprotective in stroke. Pharmacological inhibition of CaMKK exacerbated ou... read more here.
Keywords: kinase; camkk; wp254 inhibition; calcium ... See more keywords
Botanical Formulation HX109 Ameliorates TP-Induced Benign Prostate Hyperplasia in Rat Model and Inhibits Androgen Receptor Signaling by Upregulating Ca2+/CaMKKβ and ATF3 in LNCaP Cells
Sign Up to like & getrecommendations! Published in 2018 at "Nutrients"
DOI: 10.3390/nu10121946
Abstract: Benign prostatic hyperplasia (BPH) is a common disease in the elderly male population throughout the world. Among other factors, androgen dysregulation has been known to play major roles in its pathogenesis. HX109 is a botanical… read more here.
Keywords: prostate hyperplasia; hx109; botanical formulation; camkk ... See more keywords