Imaging cAMP nanodomains in the heart
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical Society Transactions"
DOI: 10.1042/bst20190245
Abstract: 3′-5′-cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger that modulates multiple cellular functions. It is now well established that cAMP can mediate a plethora of functional effects via a complex system of local regulatory… read more here.
Keywords: nanodomains heart; heart; imaging camp; camp ... See more keywords
Integrated Proteomics Unveils Nuclear PDE3A2 as a Regulator of Cardiac Myocyte Hypertrophy
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DOI: 10.1161/circresaha.122.321448
Abstract: Background: Signaling by cAMP is organized in multiple distinct subcellular nanodomains regulated by cAMP-hydrolyzing PDEs (phosphodiesterases). Cardiac β-adrenergic signaling has served as the prototypical system to elucidate cAMP compartmentalization. Although studies in cardiac myocytes have… read more here.
Keywords: camp nanodomains; camp; integrated proteomics; cardiac myocyte ... See more keywords