Anagrelide: A Clinically Effective cAMP Phosphodiesterase 3A Inhibitor with Molecular Glue Properties.
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DOI: 10.1021/acsmedchemlett.3c00092
Abstract: The mode of action by which the orphan drug anagrelide (1), a potent cAMP phosphodiesterase 3A inhibitor, reduces blood platelet count in humans is not well understood. Recent studies indicate that 1 stabilizes a complex… read more here.
Keywords: anagrelide clinically; camp phosphodiesterase; phosphodiesterase inhibitor;