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2
Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14567
Abstract: Previously, we showed that an aberrant accumulation of activated Ras in mitochondria correlates with an increase in apoptosis. In this article, we show that lack of trehalose‐6P‐synthase, known to trigger apoptosis in Saccharomyces cerevisiae, induces localization…
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Keywords:
active ras2;
pka pathway;
regulated cell;
mitochondria ... See more keywords
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1
Published in 2020 at "Chinese Journal of Integrative Medicine"
DOI: 10.1007/s11655-020-3205-5
Abstract: Objective To investigate the mechanism of cAMP-PKA signaling pathway mediated by Chinese medicine formula Shaoyao Gancao Decoction (芍药甘草汤, SGD) on the regulation of aquaporin 5 (AQP5) and muscarinic receptor 3 (M3R) levels in Sjögren’s syndrome…
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Keywords:
medicine;
m3r;
pka signaling;
aqp5 m3r ... See more keywords
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1
Published in 2018 at "Current Biology"
DOI: 10.1016/j.cub.2018.02.048
Abstract: Summary Mitochondria play fundamental roles within cells, including energy provision, calcium homeostasis, and the regulation of apoptosis. The transport of mitochondria by microtubule-based motors is critical for neuronal structure and function. This process allows local…
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Keywords:
promotes axonal;
transport;
transport mitochondria;
camp pka ... See more keywords
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Published in 2021 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2021.174370
Abstract: Colorectal cancer (CRC) is the most fatal gastrointestinal tumor and it is urge to explore powerful drugs for the treatment. Diosgenin (DSG) as a new steroidal had been reported exerts anti-tumor activity in multiple cancers,…
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Keywords:
colorectal cancer;
crc;
pka creb;
camp pka ... See more keywords
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Published in 2017 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2017.08.006
Abstract: BACKGROUND Guanosine is a natural product and an endogenous nucleoside that has shown to increase during myocardial ischemia. Platelets are critically involved in ischemic coronary events. It remains unknown, however, whether guanosine may affect platelet…
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Keywords:
guanosine;
antithrombotic properties;
activation;
camp pka ... See more keywords
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3
Published in 2022 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2022.115310
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Areca Thirteen Pill, also called Gao You-13 (GY-13), is a traditional Mongolian herbal formula and has been extensively used to treat depression in Mongolian areas, which belongs to Heyi disease in Mongolian medicine.…
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Keywords:
bdnf;
medicine;
camp pka;
depression ... See more keywords
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1
Published in 2017 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2016.10.008
Abstract: In human adrenal, serotonin (5-HT), produced by mast cells located in zona glomerulosa, stimulates production of corticosteroids through a paracrine mechanism involving the 5-HT receptor type 4 (5-HT4). The aim of the present study was…
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Keywords:
adrenocortical cells;
human adrenocortical;
type calcium;
calcium ... See more keywords
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Published in 2020 at "Redox Biology"
DOI: 10.1016/j.redox.2020.101747
Abstract: Meteorin-like (METRNL) protein is a newly identified myokine that functions to modulate energy expenditure and inflammation in adipose tissue. Herein, we aim to investigate the potential role and molecular basis of METRNL in doxorubicin (DOX)-induced…
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Keywords:
metrnl;
camp pka;
induced cardiotoxicity;
dox ... See more keywords
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1
Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-33352-8
Abstract: Melanogenesis is the process of production of melanin pigments that are responsible for the colors of skin, eye, and hair and provide protection from ultraviolet radiation. However, excessive levels of melanin formation cause hyperpigmentation disorders…
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Keywords:
pka creb;
melanogenesis;
camp pka;
p38 mapk ... See more keywords
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1
Published in 2022 at "Environmental microbiology"
DOI: 10.1111/1462-2920.16089
Abstract: NADPH oxidases (NOXs) and hydrogen peroxide (H2 O2 ) are involved in physiological and pathological processes, and cell fate decisions in organisms. However, regulatory mechanism of NOXs and the role of H2 O2 on fungal…
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Keywords:
sexual reproduction;
reproduction host;
host infection;
camp pka ... See more keywords
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1
Published in 2023 at "Photochemistry and photobiology"
DOI: 10.1111/php.13813
Abstract: Intrauterine adhesion (IUA), a major cause of uterine infertility, is pathologically characterized by endometrial fibrosis. Current treatments for IUA have poor efficacy with high recurrence rate, and restoring uterine functions is difficult. We aimed to…
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Keywords:
pka creb;
pbm;
therapy;
camp pka ... See more keywords