Gramine-based structure optimization to enhance anti-gastric cancer activity.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.104549
Abstract: Gramine is a natural indole alkaloid with a wide range of biological activities, but its anti-gastric cancer activity is poor. Herein, a pharmacophore fusion strategy was adopted to design and synthesize a new series of… read more here.
Keywords: gastric cancer; cancer; gramine based; anti gastric ... See more keywords
Application of nano/microencapsulated phenolic compounds against cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in colloid and interface science"
DOI: 10.1016/j.cis.2020.102153
Abstract: Nowadays, polyphenols as bioactive compounds are being used in producing anti-cancer drugs. Low stability against harsh environmental conditions, untargeted release, low solubility, and low absorption of pure phenolic molecules are significant barriers, which decrease the… read more here.
Keywords: application nano; cancer; anti cancer; phenolic molecules ... See more keywords
E-waste based graphene oxide/V2O5/Pt ternary composite: Enhanced visible light driven photocatalyst for anti-microbial and anti-cancer activity
Sign Up to like & getrecommendations! Published in 2020 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"
DOI: 10.1016/j.colsurfa.2020.125469
Abstract: Abstract Microbial water pollution has gained increased attention due to its detrimental effects on humans and to the planet. Photocatalytic disinfection is reported as an efficient method for the treatment of microbial polluted waters. The… read more here.
Keywords: graphene oxide; disinfection; v2o5; anti cancer ... See more keywords
Curcumin composite particles prepared by spray drying and in vitro anti-cancer activity on lung cancer cell line
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2018.04.006
Abstract: Abstract This study was aimed to prepare curcumin composite particles by spray drying to improve the dissolution of curcumin and subsequently to determine the anti-cancer activity of the composite particles. The composite particles containing various… read more here.
Keywords: curcumin; composite particles; cancer; anti cancer ... See more keywords
Self-Assembly, Tunable Hydrogel Properties, and Selective Anti-Cancer Activity of a Carnosine-Derived Lipidated Peptide
Sign Up to like & getrecommendations! Published in 2019 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.9b09065
Abstract: A novel lipopeptide C16KTTβAH was designed that incorporates the KTT tripeptide sequence from “Matrixyl” lipopeptides along with the bioactive βAH (β-alanine-histidine) carnosine dipeptide motif, attached to a C16 hexadecyl lipid chain. We show that this… read more here.
Keywords: self assembly; anti cancer; cancer; concentration ... See more keywords
A combined treatment with melatonin and andrographis promotes autophagy and anti-cancer activity in colorectal cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Carcinogenesis"
DOI: 10.1093/carcin/bgac008
Abstract: Colorectal cancer (CRC) is one of the most frequent malignancies worldwide and remains one of the leading causes of cancer-related deaths in the United States. The high degree of morbidity and mortality associated with this… read more here.
Keywords: cancer; treatment; cancer activity; anti cancer ... See more keywords
Ginseng mediates its anti-cancer activity by inhibiting the expression of DNMTs and reactivating methylation-silenced genes in colorectal cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Carcinogenesis"
DOI: 10.1093/carcin/bgad025
Abstract: Developing safe and effective therapeutic modalities remains a critical challenge for improving the prognosis of patients with colorectal cancer (CRC). In this regard, targeting epigenetic regulation in cancers has recently emerged as a promising therapeutic… read more here.
Keywords: methylation; cancer activity; anti cancer; ginseng ... See more keywords
A novel curcuminoid-tea polyphenol formulation: Preparation, characterization, and in vitro anti-cancer activity
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Food Biochemistry"
DOI: 10.1111/jfbc.12332
Abstract: Curcuminoids and tea polyphenols (CTP) are nutraceuticals with anticancer activity. To evaluate their combined in vitro anti-cancer activity, the CTP mixture was loaded on solid lipid nanoparticles (SLNPs). The resulting CTP-SLNPs were characterized and shown… read more here.
Keywords: ctp slnps; formulation; cancer; anti cancer ... See more keywords
Anti-cancer activity of pyridoxal phosphate and metformin combination in human pancreatic cancer cells.
Sign Up to like & getrecommendations! Published in 2022 at "Nutrition and health"
DOI: 10.1177/02601060221137624
Abstract: Background: Pancreatic cancer is the foremost cause of cancer-related deaths in many developed countries with a poor prognosis. With advanced disease conditions chemotherapy, surgery followed by radiation is the regimen to prolong the survival. But… read more here.
Keywords: pancreatic cancer; cancer activity; anti cancer; metformin ... See more keywords
Cell-Free Supernatant of Odoribacter splanchnicus Isolated From Human Feces Exhibits Anti-colorectal Cancer Activity
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.736343
Abstract: The gut microbiota (GM) has been shown to be closely associated with the development of colorectal cancer (CRC). However, the involvement of GM is CRC has mainly been demonstrated by metagenomic profiling studies showing the… read more here.
Keywords: cancer; cell free; splanchnicus; cancer activity ... See more keywords
HZ-A-018, a novel inhibitor of Bruton tyrosine kinase, exerts anti-cancer activity and sensitizes 5-FU in gastric cancer cells
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1142127
Abstract: Gastric cancer is the third leading cause of cancer related death worldwide. Due to the complexity and heterogeneity of gastric cancer, the development of targeted drugs is somehow limited, but is urgently needed. Since the… read more here.
Keywords: cancer; cancer activity; anti cancer; gastric cancer ... See more keywords