Cancer‐associated V‐ATPase induces delayed apoptosis of protumorigenic neutrophils
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12630
Abstract: Tumors and neutrophils undergo an unexpected interaction, in which products released by tumor cells interact to support neutrophils that in turn support cancer growth, angiogenesis, and metastasis. A key protein that is highly expressed by… read more here.
Keywords: cancer; cancer associated; delayed apoptosis; protumorigenic neutrophils ... See more keywords
Enhancing cancer‐associated fibroblast fatty acid catabolism within a metabolically challenging tumor microenvironment drives colon cancer peritoneal metastasis
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12917
Abstract: Most cancer‐related deaths result from the progressive growth of metastases. Patients with peritoneal metastatic (PM) colorectal cancer have reduced overall survival. Currently, it is still unclear why colorectal cancer (CRC) cells home to and proliferate… read more here.
Keywords: fatty acid; colorectal cancer; colon cancer; cancer ... See more keywords
Cancer‐associated fibroblast migration in non‐small cell lung cancers is modulated by increased integrin α11 expression
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12937
Abstract: Cancer‐associated fibroblasts (CAFs) regulate cancer progression through the modulation of extracellular matrix (ECM) and cancer cell adhesion. While undergoing a series of phenotypic changes, CAFs control cancer–stroma interactions through integrin receptor signaling. Here, we isolated… read more here.
Keywords: cancer stroma; expression; non small; cancer ... See more keywords
LAMC1 upregulation via TGFβ induces inflammatory cancer-associated fibroblasts in esophageal squamous cell carcinoma via NF-κB-CXCL1-STAT3.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular oncology"
DOI: 10.1002/1878-0261.13053
Abstract: Cancer-associated fibroblasts (CAFs) are a heterogenous cell population within the tumor microenvironment, and play an important role in tumor development. By regulating the heterogeneity of CAFs, transforming growth factor β (TGFβ) influences tumor development. Here,… read more here.
Keywords: associated fibroblasts; tgf; cancer associated; cell ... See more keywords
Analyzing the role of cancer-associated fibroblast activation on macrophage polarization.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular oncology"
DOI: 10.1002/1878-0261.13454
Abstract: Snail1 is a transcriptional factor required for cancer-associated fibroblast (CAF) activation, and mainly detected in CAFs in human tumors. In the mouse mammary tumor virus-polyoma middle tumor-antigen (MMTV-PyMT) model of murine mammary gland tumors, Snai1… read more here.
Keywords: cafs; polarization; cancer associated; tumor ... See more keywords
Rapid Capture of Cancer Extracellular Vesicles by Lipid Patch Microarrays.
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DOI: 10.1002/adma.202008493
Abstract: Extracellular vesicles (EVs) contain various bioactive molecules such as DNA, RNA, and proteins, and play a key role in the regulation of cancer progression. Furthermore, cancer-associated EVs carry specific biomarkers and can be used in… read more here.
Keywords: extracellular vesicles; associated evs; rapid capture; cancer ... See more keywords
Anticoagulant treatment of cancer‐associated venous thromboembolism: Interpreting real‐world data with caution
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DOI: 10.1002/ajh.25164
Abstract: No abstract is available for this article. This article is protected by copyright. All rights reserved. read more here.
Keywords: associated venous; venous thromboembolism; thromboembolism interpreting; treatment cancer ... See more keywords
Cancer‐associated fibroblasts in breast cancer: Challenges and opportunities
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DOI: 10.1002/cac2.12291
Abstract: The tumor microenvironment is proposed to contribute substantially to the progression of cancers, including breast cancer. Cancer‐associated fibroblasts (CAFs) are the most abundant components of the tumor microenvironment. Studies have revealed that CAFs in breast… read more here.
Keywords: fibroblasts breast; breast cancer; associated fibroblasts; cancer associated ... See more keywords
Cancer associated thrombosis and mortality in patients with cancer stratified by khorana score risk levels
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DOI: 10.1002/cam4.3437
Abstract: The Khorana score (KS) clinical algorithm is used to predict VTE risk in cancer patients. The study objective was to evaluate VTE and survival rates among patients newly diagnosed with cancer and stratified by KS… read more here.
Keywords: cancer stratified; khorana score; risk; cancer ... See more keywords
Pi‐Class Glutathione S‐transferase (GSTP1)‐Selective Fluorescent Probes for Multicolour Imaging with Various Cancer‐Associated Enzymes
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DOI: 10.1002/cbic.202200443
Abstract: Pi‐class glutathione S‐transferase (GSTP1) is highly expressed in a wide variety of human cancer tissues compared to the corresponding normal counterpart. Therefore, GSTP1 is a potential target enzyme for overcoming resistance to chemotherapeutic agents or… read more here.
Keywords: cancer; cancer associated; class glutathione; fluorescent probes ... See more keywords
Cost‐effectiveness analysis of low‐dose direct oral anticoagulant (DOAC) for the prevention of cancer‐associated thrombosis in the United States
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DOI: 10.1002/cncr.32724
Abstract: Randomized controlled trials (RCTs) have demonstrated that low‐dose direct oral anticoagulants (DOACs), including rivaroxaban and apixaban, may help reduce the incidence of cancer‐associated venous thromboembolism (VTE). read more here.
Keywords: low dose; direct oral; dose direct; cancer ... See more keywords