Pilot study of oral metformin in cancer‐bearing cats
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary and Comparative Oncology"
DOI: 10.1111/vco.12169
Abstract: A prospective dose escalation pilot study was performed in cancer-bearing cats to assess toxicity and surrogate biomarkers of pharmacologic activity of oral metformin hydrochloride. Nine cats with measurable spontaneous cancer were treated with oral metformin… read more here.
Keywords: oral metformin; pilot study; metformin; cancer bearing ... See more keywords
Monitoring treatment effects in lung cancer-bearing mice: clinical CT and clinical MRI compared to micro-CT
Sign Up to like & getrecommendations! Published in 2020 at "European Radiology Experimental"
DOI: 10.1186/s41747-020-00160-7
Abstract: Background Compared to histology-based methods, imaging can reduce animal usage in preclinical studies. However, availability of dedicated scanners is limited. We evaluated clinical computed tomography (CT) and magnetic resonance imaging (MRI) in comparison to dedicated… read more here.
Keywords: treatment; cancer bearing; mri; lung cancer ... See more keywords
Anti-tumor effects of PEGylated-nanoliposomes containing ginger extract in colorectal cancer-bearing mice
Sign Up to like & getrecommendations! Published in 2022 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2022.63870.14075
Abstract: Objective(s): This study aimed to develop a nanoliposomal formulation containing ginger ethanolic extract with a higher therapeutic effect for cancer treatment. Materials and Methods: The present study aimed to prepare PEGylated nanoliposomal ginger through the… read more here.
Keywords: ginger; colorectal cancer; containing ginger; tumor ... See more keywords
CCR4 Blockade Diminishes Intratumoral Macrophage Recruitment and Augments Survival of Syngeneic Pancreatic Cancer-Bearing Mice
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11061517
Abstract: Pancreatic cancer is known for its tumor microenvironment (TME), which is rich in stromal and immune cells supporting cancer growth and therapy resistance. In particular, tumor-associated macrophages (TAMs) are known for their angiogenesis- and metastasis-promoting… read more here.
Keywords: pancreatic cancer; blockade; mice; cancer bearing ... See more keywords