Targeting PD-1 in cancer: Biological insights with a focus on breast cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Critical reviews in oncology/hematology"
DOI: 10.1016/j.critrevonc.2019.07.011
Abstract: Programmed cell death-1 (PD-1) receptor and its ligands physiologically regulate the activity of the adaptive immune system to limit excessive inflammatory processes, thus preventing normal tissue damage. Tumor cells escape from the host immune surveillance… read more here.
Keywords: targeting cancer; cancer biological; biological insights; breast cancer ... See more keywords
Inhibition of galectins in cancer: Biological challenges for their clinical application
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1104625
Abstract: Galectins play relevant roles in tumor development, progression and metastasis. Accordingly, galectins are certainly enticing targets for medical intervention in cancer. To date, however, clinical trials based on galectin inhibitors reported inconclusive results. This review… read more here.
Keywords: biological challenges; challenges clinical; cancer biological; galectins cancer ... See more keywords
Validation of ESM1 Related to Ovarian Cancer and the Biological Function and Prognostic Significance
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DOI: 10.7150/ijbs.66839
Abstract: Background: Ovarian cancer (OC), a serious gynecological malignant disease, remains an enormous challenge in early diagnosis and medical treatment. Based on the GEO and TCGA databases in R language, endothelial cell-specific molecule 1 (ESM1) was… read more here.
Keywords: ovarian cancer; cancer biological; related ovarian; esm1 related ... See more keywords