Animal Models of Breast Cancer Bone Metastasis.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8997-3_17
Abstract: This chapter is designed to provide a comprehensive overview outlining the different in vivo models available for research into breast cancer bone metastasis. The main focus is to guide the researcher through the methodological processes… read more here.
Keywords: cancer bone; bone metastasis; breast cancer;
A rare insight into the immunosuppressive landscape of prostate cancer bone metastases.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer cell"
DOI: 10.1016/j.ccell.2021.09.004
Abstract: Therapeutic options for metastatic prostate cancer patients are currently limited. In this issue of Cancer Cell, Kfoury et al. characterized the tumor and immune compartments of prostate cancer bone metastasis, revealing a mechanism of immunosuppression that… read more here.
Keywords: cancer; cancer bone; rare insight; prostate cancer ... See more keywords
Analysis of genomics and immune infiltration patterns of epithelial-mesenchymal transition related to metastatic breast cancer to bone
Sign Up to like & getrecommendations! Published in 2020 at "Translational Oncology"
DOI: 10.1016/j.tranon.2020.100993
Abstract: Highlights • Differential expression analysis showed a total of 304 differentially expressed genes, which were mainly related to proteoglycans in cancer, the PI3K/Akt signaling pathway, and the TGF-beta signaling pathway.• The survival-related linear risk assessment… read more here.
Keywords: infiltration patterns; breast cancer; immune infiltration; cancer ... See more keywords
Translational models of prostate cancer bone metastasis
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DOI: 10.1038/s41585-018-0020-2
Abstract: Metastatic disease is the principal cause of prostate-cancer-related mortality. Our ability to accurately recapitulate the spread of prostate cancer to bone — the most common site of metastasis — is critical to the development of… read more here.
Keywords: metastasis; cancer bone; bone metastasis; prostate cancer ... See more keywords
Analysis of Related Risk Factors and Prognostic Factors of Gastric Cancer with Bone Metastasis: A SEER-Based Study
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DOI: 10.1155/2022/3251051
Abstract: Background Gastric cancer is among the most common malignant tumors at home and abroad, because its early symptoms are mostly insidious, which leads to distant metastasis when gastric cancer is first diagnosed. The common metastatic… read more here.
Keywords: bone metastasis; cancer bone; cancer; gastric cancer ... See more keywords
Efficacy of extracranial stereotactic body radiation therapy (SBRT) added to standard treatment in patients with solid tumors (breast, prostate and non-small cell lung cancer) with up to 3 bone-only metastases: study protocol for a randomised phase III trial (STEREO-OS)
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DOI: 10.1186/s12885-021-07828-2
Abstract: Background Stereotactic Body Radiation Therapy (SBRT) is an innovative modality based on high precision planning and delivery. Cancer with bone metastases and oligometastases are associated with an intermediate or good prognosis. We assume that prolonged survival… read more here.
Keywords: cancer bone; treatment; sbrt; bone metastases ... See more keywords
Quantitative bone SPECT/CT: high specificity for identification of prostate cancer bone metastases
Sign Up to like & getrecommendations! Published in 2019 at "BMC Musculoskeletal Disorders"
DOI: 10.1186/s12891-019-3001-6
Abstract: PurposeBone scintigraphy with 99mTc-labeled diphosphonates can identify prostate cancer bone metastases with high sensitivity, but relatively low specificity, because benign conditions such as osteoarthritis can also trigger osteoblastic reactions. We aimed to investigate the diagnostic… read more here.
Keywords: bone metastases; prostate cancer; bone; spinal pelvic ... See more keywords
In vivo SELEX of bone targeting aptamer in prostate cancer bone metastasis model
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s188003
Abstract: Purpose PB is one of the most severe complications of late stage prostate cancer and negatively impacts patient quality of life. A major challenge for the treatment of cancer bone metastasis is the management of… read more here.
Keywords: vivo selex; cancer bone; prostate cancer; bone targeting ... See more keywords
Docetaxel and fluorouracil as first-line therapy for gastric cancer with bone marrow metastasis and disseminated intravascular coagulation.
Sign Up to like & getrecommendations! Published in 2022 at "Future oncology"
DOI: 10.2217/fon-2022-0748
Abstract: Gastric cancer with bone marrow metastasis and disseminated intravascular coagulation constitutes a highly aggressive gastric cancer subtype which presents a peculiar biological behavior and very poor prognosis. Retrospective studies have shown chemotherapy could prolong survival,… read more here.
Keywords: bone marrow; gastric cancer; marrow metastasis; cancer bone ... See more keywords
Clinicopathological Features, Prognostic Factors and Survival in Patients With Pancreatic Cancer Bone Metastasis
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DOI: 10.3389/fonc.2022.759403
Abstract: Purpose The purpose of this study is to reveal the clinicopathological features and identify risk factors of prognosis among patients with pancreatic cancer bone metastasis (PCBM). Patients and Methods Patients with PCBM were retrieved from… read more here.
Keywords: metastasis; pancreatic cancer; clinicopathological features; patients pancreatic ... See more keywords
Novel Methods of Targeting IL-1 Signalling for the Treatment of Breast Cancer Bone Metastasis
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DOI: 10.3390/cancers14194816
Abstract: Simple Summary The pro-inflammatory cytokine, IL1β, plays a pivotal role in breast cancer bone metastasis. Inhibiting IL-1 signalling with the IL1β specific antibody, Canakinumab, or the IL1R1 antagonist Anakinra almost eliminates bone metastases but has… read more here.
Keywords: metastasis; bone; bone metastasis; breast cancer ... See more keywords