Oxidative stress and dietary phytochemicals: Role in cancer chemoprevention and treatment.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer letters"
DOI: 10.1016/j.canlet.2017.11.002
Abstract: Several epidemiological observations have shown an inverse relation between consumption of plant-based foods, rich in phytochemicals, and incidence of cancer. Phytochemicals, secondary plant metabolites, via their antioxidant property play a key role in cancer chemoprevention… read more here.
Keywords: cancer; cancer chemoprevention; role; oxidative stress ... See more keywords
Cancer chemoprevention revisited: Cytochrome P450 family 1B1 as a target in the tumor and the microenvironment.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer treatment reviews"
DOI: 10.1016/j.ctrv.2017.10.013
Abstract: Cancer chemoprevention is the use of synthetic, natural or biological agents to prevent or delay the development or progression of malignancies. Intriguingly, many phytochemicals with anti-inflammatory and anti-angiogenic effects, recently proposed as chemoprevention strategies, are… read more here.
Keywords: cancer chemoprevention; chemoprevention; family; cancer ... See more keywords
Astragaloside in cancer chemoprevention and therapy
Sign Up to like & getrecommendations! Published in 2023 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000002661
Abstract: Abstract Tumor chemoprevention and treatment are two approaches aimed at improving the survival of patients with cancers. An ideal anti-tumor drug is that which not only kills tumor cells but also alleviates tumor-causing risk factors,… read more here.
Keywords: cancer chemoprevention; chemoprevention; astragaloside cancer; chemoprevention therapy ... See more keywords
The 4Ps of Breast Cancer Chemoprevention: Putting Proven Principles into Practice
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Prevention Research"
DOI: 10.1158/1940-6207.capr-17-0026
Abstract: The pioneering Royal Marsden Tamoxifen Prevention Trial recruited 2,471 eligible high-risk women to be randomized to either placebo or tamoxifen (20 mg daily) for 8 years. Breast cancer incidence was evaluated at a median of… read more here.
Keywords: cancer; cancer chemoprevention; 4ps breast; breast cancer ... See more keywords
Precision cut lung slices as a preclinical model for non-small cell lung cancer chemoprevention.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer prevention research"
DOI: 10.1158/1940-6207.capr-23-0004
Abstract: Lung cancer chemoprevention is critical to addressing cancer burden in high-risk populations. Chemoprevention clinical trials rely on data from pre-clinical models however, in vivo studies have high financial, technical, and staffing requirements. Precision cut lung… read more here.
Keywords: lung cancer; cancer chemoprevention; lung; chemoprevention ... See more keywords
Multifunctional role of Nobiletin in cancer chemoprevention.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2022.68.7.33
Abstract: The diversity of highly bioactive and pharmacologically active natural products which recognize essential biological targets having exquisite specificity, constitutes a massive pharmacological database for discovery of valuable drugs. The rapid accumulation of information has revealed… read more here.
Keywords: cancer chemoprevention; role; nobiletin cancer; role nobiletin ... See more keywords
Cancer Chemoprevention: Classic and Epigenetic Mechanisms Inhibiting Tumorigenesis. What Have We Learned So Far?
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2018.00644
Abstract: Cancers derive from step by step processes which are differentiated by the progressively accumulated mutations. For some tumors there is a clear progressive advancement from benign lesions to malignancy and for these, preventive screening programs… read more here.
Keywords: cancer chemoprevention; chemoprevention; epigenetic mechanisms; cancer ... See more keywords
Assessing the Current State of Lung Cancer Chemoprevention: A Comprehensive Overview
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12051265
Abstract: Chemoprevention of lung cancer is thought to significantly reduce the risk of acquiring these conditions in the subpopulation of patients with underlying health issues, such as chronic obstructive pulmonary disorder and smoking-associated lung problems. Many… read more here.
Keywords: cancer chemoprevention; chemoprevention; assessing current; lung cancer ... See more keywords
Pathways Affected by Falcarinol-Type Polyacetylenes and Implications for Their Anti-Inflammatory Function and Potential in Cancer Chemoprevention
Sign Up to like & getrecommendations! Published in 2023 at "Foods"
DOI: 10.3390/foods12061192
Abstract: Polyacetylene phytochemicals are emerging as potentially responsible for the chemoprotective effects of consuming apiaceous vegetables. There is some evidence suggesting that polyacetylenes (PAs) impact carcinogenesis by influencing a wide variety of signalling pathways, which are… read more here.
Keywords: pathways affected; falcarinol type; cancer chemoprevention; cancer ... See more keywords
Lunasin and Its Epigenetic Impact in Cancer Chemoprevention
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24119187
Abstract: Cancer diseases are a leading cause of death worldwide. Therefore, it is pivotal to search for bioactive dietary compounds that can avert tumor development. A diet rich in vegetables, including legumes, provides chemopreventive substances, which… read more here.
Keywords: impact cancer; epigenetic impact; cancer chemoprevention; anti cancer ... See more keywords
Development of Genistein Drug Delivery Systems Based on Bacterial Nanocellulose for Potential Colorectal Cancer Chemoprevention: Effect of Nanocellulose Surface Modification on Genistein Adsorption
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27217201
Abstract: Genistein is an isoflavone with antioxidant, anti-inflammatory, and anticancer properties. That said, its use in the industry is limited by its low solubility in aqueous systems. In this work, bacterial nanocellulose (BNC) and BNC modified… read more here.
Keywords: adsorption; modification; cancer chemoprevention; bacterial nanocellulose ... See more keywords