Translesion synthesis inhibitors as a new class of cancer chemotherapeutics
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DOI: 10.1080/13543784.2021.1850692
Abstract: ABSTRACT Introduction: Translesion synthesis (TLS) is a DNA damage tolerance mechanism that replaces the replicative DNA polymerase with a specialized, low-fidelity TLS DNA polymerase that can copy past DNA lesions during active replication. Recent studies… read more here.
Keywords: cancer chemotherapeutics; new class; dna; translesion synthesis ... See more keywords