Persistent Endoplasmic Reticulum Stress Stimulated by Peptide Assemblies for Sensitizing Cancer Chemotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202039
Abstract: Pharmacological targeting of endoplasmic reticulum (ER) stress represents one of important methods for disease therapy, which, however, is significantly suppressed by the ER homeostatic processe. Herein, a proof‐of‐concept strategy is reported for persistent stimulation of… read more here.
Keywords: endoplasmic reticulum; peptide assemblies; cancer chemotherapy; stress ... See more keywords
Religiosity and Beliefs About the Transmission of Cancer, Chemotherapy, and Radiation Through Physical Contact in Saudi Arabia
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Religion and Health"
DOI: 10.1007/s10943-018-00745-y
Abstract: We examined relationships between religiosity and Saudi cancer patients’ beliefs about the spread of cancer, chemotherapy, and radiation therapy through close physical contact. Surveyed were 64 patients seen in university oncology clinics. Assessed were beliefs… read more here.
Keywords: religiosity; chemotherapy radiation; saudi; cancer chemotherapy ... See more keywords
A Preliminary Study in Search of Potential Peptide Candidates for a Combinational Therapy with Cancer Chemotherapy Drug
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Peptide Research and Therapeutics"
DOI: 10.1007/s10989-017-9646-9
Abstract: Cancer which caused by the growth and spreading of abnormal cells in an uncontrolled manner remains a major cause of death affecting millions of people. The current cancer chemotherapy treatment modalities have several disadvantages, mostly… read more here.
Keywords: potential peptide; peptide; chemotherapy drug; cancer chemotherapy ... See more keywords
Chitosan-grafted-poly(methacrylic acid)/graphene oxide nanocomposite as a pH-responsive de novo cancer chemotherapy nanosystem.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.07.036
Abstract: The aim of this study was the design and development of a novel de novo drug delivery system for cancer chemotherapy. For this purpose, chitosan (CS) functionalized using phthalic anhydride followed by 4-cyano, 4-[(phenylcarbothioyl) sulfanyl]… read more here.
Keywords: graphene oxide; poly methacrylic; methacrylic acid; cancer chemotherapy ... See more keywords
The camouflage of graphene oxide by red blood cell membrane with high dispersibility for cancer chemotherapy.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2021.01.088
Abstract: Cancer is a serious threat to human health. Graphene oxide (GO) is a good carrier for cancer treatment due to its large surface area and high drug loading, while it's unstable under physiological conditions with… read more here.
Keywords: graphene oxide; red blood; blood cell; cancer chemotherapy ... See more keywords
Photoreactive Mercury-Containing Metallosupramolecular Nanoparticles with Tailorable Properties That Promote Enhanced Cellular Uptake for Effective Cancer Chemotherapy.
Sign Up to like & getrecommendations! Published in 2023 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c01369
Abstract: A new potential route to enhance the efficiency of supramolecular polymers for cancer chemotherapy was successfully demonstrated by employing a photosensitive metallosupramolecular polymer (Hg-BU-PPG) containing an oligomeric poly(propylene glycol) backbone and highly sensitive pH-responsive uracil-mercury-uracil… read more here.
Keywords: cancer; cellular uptake; cancer chemotherapy; cancer cells ... See more keywords
Simplified Derivatives of Tetrandrine as Potent and Specific P-gp Inhibitors to Reverse Multidrug Resistance in Cancer Chemotherapy.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c02061
Abstract: Targeted inhibition of a drug efflux transporter P-glycoprotein (P-gp) is an important strategy to reverse multidrug resistance in cancer chemotherapy. In this study, a rationally structural simplification to natural tetrandrine was performed based on molecular… read more here.
Keywords: resistance cancer; multidrug resistance; reverse multidrug; cancer chemotherapy ... See more keywords
Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-11718-4
Abstract: Developing biomimetic nanoparticles without loss of the integrity of proteins remains a major challenge in cancer chemotherapy. Here, we develop a biocompatible tumor-cell-exocytosed exosome-biomimetic porous silicon nanoparticles (PSiNPs) as drug carrier for targeted cancer chemotherapy.… read more here.
Keywords: drug; dox psinps; cancer chemotherapy; cancer ... See more keywords
Risk of solid cancer after chemotherapy
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Urology"
DOI: 10.1038/s41585-018-0085-y
Abstract: Platinum-based chemotherapy continues to be linked with the subsequent development of various solid tumours. In a large analytical study of >5,800 survivors of testicular cancer, Groot and colleagues observed statistically significant dose-dependent increases in gastrointestinal cancer… read more here.
Keywords: chemotherapy; risk solid; urology; cancer chemotherapy ... See more keywords
Halogenated derivatives of methotrexate as human dihydrofolate reductase inhibitors in cancer chemotherapy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2019.1591302
Abstract: Abstract Methotrexate is a widely used anti-metabolite in cancer chemotherapy. A series of halogenated drugs is designed from Methotrexate to assess their interactions with human dihydrofolate reductase. The aim of this study is to evaluate… read more here.
Keywords: modified drugs; molecular dynamics; dihydrofolate reductase; cancer chemotherapy ... See more keywords
Complex polymeric nanomicelles co-delivering doxorubicin and dimethoxycurcumin for cancer chemotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery"
DOI: 10.1080/10717544.2022.2073403
Abstract: Abstract Combinational therapy is a new trend in medical sciences to achieve a maximum therapeutic response of the drugs with a comparatively low incidence of severe adverse effects. To overcome the challenges of conventional formulations… read more here.
Keywords: dimethoxycurcumin; cancer chemotherapy; drug; complex polymeric ... See more keywords