Cancer-on-a-Chip: Models for Studying Metastasis
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DOI: 10.3390/cancers14030648
Abstract: Simple Summary Microfluidic-based cancer-on-a-chip models are powerful tools to study the tumor microenvironment (TME). Two-dimensional cell culture cannot recapitulate TME. In vivo animal models can better represent the TME, but their physiology is vastly different… read more here.
Keywords: metastasis; cancer chip; chip models; tumor ... See more keywords
The Effect of Dynamic, In Vivo-like Oxaliplatin on HCT116 Spheroids in a Cancer-on-Chip Model Is Representative of the Response in Xenografts
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DOI: 10.3390/mi13050739
Abstract: The cancer xenograft model in which human cancer cells are implanted in a mouse is one of the most used preclinical models to test the efficacy of novel cancer drugs. However, the model is imperfect;… read more here.
Keywords: cancer; cancer chip; xenograft; model ... See more keywords