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Published in 2020 at "Molecular aspects of medicine"
DOI: 10.1016/j.mam.2020.100860
Abstract: Iron plays an essential role in normal biological processes: The generation of cellular energy, oxygen transport, DNA synthesis and repair are all processes that require iron-coordinated proteins, either as elemental iron, heme or iron-sulfur clusters.…
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Keywords:
cancer;
iron;
iron cancer;
cancer connection ... See more keywords
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Published in 2024 at "Nucleus"
DOI: 10.1080/19491034.2024.2321265
Abstract: ABSTRACT Promyelocytic leukemia (PML) nuclear bodies, membrane-less organelles in the nucleus, play a crucial role in cellular homeostasis. These dynamic structures result from the assembly of scaffolding PML proteins and various partners. Recent crystal structure…
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Keywords:
bodies cancer;
pml bodies;
pml nuclear;
cancer connection ... See more keywords
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Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-sy21-02
Abstract: Obesity is the second leading modifiable risk factor for many cancers, behind only smoking. It can, however, also provide a benefit and increase responses and outcomes to checkpoint immune therapies. To understand this paradox and…
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Keywords:
cancer;
obesity;
cancer connection;
inflammatory drivers ... See more keywords
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Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.831657
Abstract: The high level of serum cholesterol caused by the excessive absorption of cholesterol can lead to hypercholesteremia, thus promoting the occurrence and development of cancer. Ezetimibe is a drug that reduces cholesterol absorption and has…
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Keywords:
cancer connection;
ezetimibe cancer;
cholesterol;
absorption ... See more keywords