Autophosphorylation of the carboxyl‐terminal domain is not required for oncogenic transformation by lung‐cancer derived EGFR mutants
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Cancer"
DOI: 10.1002/ijc.31332
Abstract: Aberrant activation of cancer‐derived mutants of the epidermal growth factor receptor (EGFR) is closely associated with cancer pathogenesis and is thought to be mediated through multiple tyrosine phosphorylations within the C‐terminal domain. Here, we examined… read more here.
Keywords: autophosphorylation; transformation; cancer derived; lung cancer ... See more keywords
Breast cancer‐derived exosomes: Tumor progression and therapeutic agents
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29668
Abstract: Tumor cells secrete extracellular vesicles (EVs) for intercellular communication. EVs by transporting different proteins, nucleic acids, and lipids contribute to affect target cell function and fate. EVs which originate directly from multivesicular bodies so‐called exosomes… read more here.
Keywords: tumor progression; breast cancer; cancer derived; cancer ... See more keywords
Amyloidosis: A cancer-derived paraproteinemia and kidney involvement.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in medical sciences"
DOI: 10.1016/j.advms.2016.06.004
Abstract: Amyloidosis is the general term describing the extracellular tissue deposition of fibrils composed of low molecular weight subunits of a variety of proteins. There are multiple different human protein precursors of amyloid fibrils. Amyloid deposits… read more here.
Keywords: paraproteinemia kidney; amyloidosis; cancer derived; derived paraproteinemia ... See more keywords
Engineered Cancer-Derived Small Extracellular Vesicle-Liposome Hybrid Delivery System for Targeted Treatment of Breast Cancer.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c22749
Abstract: Cancer-derived small extracellular vesicles (sEVs) may be a promising drug delivery system that targets cancer cells due to their unique features, such as native homing ability, biological barrier crossing capability, and low immune response. However,… read more here.
Keywords: delivery system; ability; cancer derived; cancer ... See more keywords
Involvement of cancer-derived EMT cells in the accumulation of 18F-fluorodeoxyglucose in the hypoxic cancer microenvironment
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-88414-1
Abstract: A high rate of glycolysis, one of the most common features of cancer, is used in positron emission tomography (PET) imaging to visualize tumor tissues using 18F-fluorodeoxyglucose (18F-FDG). Heterogeneous intratumoral distribution of 18F-FDG in tissues… read more here.
Keywords: 18f fluorodeoxyglucose; accumulation; cancer microenvironment; cancer derived ... See more keywords
Cancer-derived exosomes loaded with ultrathin palladium nanosheets for targeted bioorthogonal catalysis
Sign Up to like & getrecommendations! Published in 2019 at "Nature catalysis"
DOI: 10.1038/s41929-019-0333-4
Abstract: The transformational impact of bioorthogonal chemistries has inspired new strategies for the in vivo synthesis of bioactive agents through non-natural means. Among these, Pd catalysts have played a prominent role in the growing subfield of… read more here.
Keywords: catalysis; cancer derived; cancer; bioorthogonal catalysis ... See more keywords
Combined administration of lauric acid and glucose improved cancer‐derived cardiac atrophy in a mouse cachexia model
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Science"
DOI: 10.1111/cas.14656
Abstract: Cancer‐derived myocardial damage is an important cause of death in cancer patients. However, the development of dietary interventions for treating such damage has not been advanced. Here, we investigated the effect of dietary intervention with… read more here.
Keywords: mouse cachexia; cachexia; cachexia model; cancer derived ... See more keywords
Cancer‐derived immunoglobulin G: A novel marker for differential diagnosis and relapse prediction in parathyroid carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Endocrinology"
DOI: 10.1111/cen.14158
Abstract: A differential diagnosis between malignant and benign parathyroid lesions is difficult due to their overlapping clinicopathological characteristics. As such, molecular markers are urgently needed. Cancer‐derived immunoglobulin G (CIgG) is a novel molecule playing important roles… read more here.
Keywords: differential diagnosis; cancer derived; parathyroid; derived immunoglobulin ... See more keywords
Genetic Ancestry Inference from Cancer-Derived Molecular Data across Genomic and Transcriptomic Platforms
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Research"
DOI: 10.1158/0008-5472.can-22-0682
Abstract: The development of a computational approach that enables accurate and robust ancestry inference from cancer-derived molecular profiles without matching cancer-free data provides a valuable methodology for genetic ancestry–oriented cancer research. read more here.
Keywords: ancestry inference; ancestry; derived molecular; inference cancer ... See more keywords
Abstract 5083: Using proteomics profiling to elucidate the interactions of breast cancer-derived exosomes with the blood-brain barrier
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-5083
Abstract: Breast cancer metastasis to brain is associated with a dismal prognosis commonly attributed to a limited understating of the mechanisms driving this pathological process. Elucidation of the early events leading to brain metastasis is essential… read more here.
Keywords: breast cancer; cancer derived; cancer; brain ... See more keywords
Analyses of lung cancer-derived volatiles in exhaled breath and in vitro models.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental biology and medicine"
DOI: 10.1177/15353702221082634
Abstract: Lung cancer is one of the leading causes of cancer incidence and cancer-related deaths in the world. Early diagnosis of pulmonary tumors results in improved survival compared to diagnosis with more advanced disease, yet early… read more here.
Keywords: lung cancer; cancer; cancer derived; disease ... See more keywords