Diabetes: Metformin in breast cancer
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Endocrinology"
DOI: 10.1038/nrendo.2017.37
Abstract: of Clinical Oncology reports that metformin improves the prognosis of patients with HER2-positive, hormone receptor (HR)-positive breast cancer and diabetes mellitus. The phase III randomized ALTTO trial included patients with early-stage, surgically resected HER2positive breast… read more here.
Keywords: cancer diabetes; metformin; breast cancer; diabetes mellitus ... See more keywords
Cancer and diabetes co-occurrence: A national study with 44 million person-years of follow-up
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0276913
Abstract: The number of new cases of cancer is increasing each year, and rates of diabetes mellitus are also increasing dramatically over time. It is not an unusual occurrence for an individual to have both cancer… read more here.
Keywords: years follow; person years; million person; cancer diabetes ... See more keywords
Causal associations between site-specific cancer and diabetes risk: A two-sample Mendelian randomization study
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1110523
Abstract: Background Both cancer and diabetes are complex chronic diseases that have high economic costs for society. The co-occurrence of these two diseases in people is already well known. The causal effects of diabetes on the… read more here.
Keywords: mendelian randomization; diabetes risk; site specific; cancer diabetes ... See more keywords
Emerging Roles of NDUFS8 Located in Mitochondrial Complex I in Different Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27248754
Abstract: NADH:ubiquinone oxidoreductase core subunit S8 (NDUFS8) is an essential core subunit and component of the iron-sulfur (FeS) fragment of mitochondrial complex I directly involved in the electron transfer process and energy metabolism. Pathogenic variants of… read more here.
Keywords: mitochondrial complex; different diseases; emerging roles; diabetes mellitus ... See more keywords