Multipotent Poly(Tertiary Amine‐Oxide) Micelles for Efficient Cancer Drug Delivery
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202200173
Abstract: The cancer drug delivery process involves a series of biological barriers, which require the nanomedicine to exhibit different, even opposite properties for high therapeutic efficacy. The prevailing design philosophy, i.e., integrating these properties within one… read more here.
Keywords: tertiary amine; cancer drug; poly tertiary; drug delivery ... See more keywords
Extracellular Vesicles in Cancer Drug Resistance: Roles, Mechanisms, and Implications
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DOI: 10.1002/advs.202201609
Abstract: Extracellular vesicles (EVs) are cell‐derived nanosized vesicles that mediate cell‐to‐cell communication via transporting bioactive molecules and thus are critically involved in various physiological and pathological conditions. EVs contribute to different aspects of cancer progression, such… read more here.
Keywords: extracellular vesicles; cancer drug; resistance; cancer ... See more keywords
Cancer drug wastage: The hidden cost in value‐based cancer care delivery
Sign Up to like & getrecommendations! Published in 2017 at "Cancer"
DOI: 10.1002/cncr.30805
Abstract: In this issue of Cancer, Truong et al highlight the potentially significant contribution of cancer drug wastage to the overall cost of cancer care delivery. This can be considered a hidden cost because most oncology… read more here.
Keywords: cost; drug; cancer; drug wastage ... See more keywords
Cancer drug shortages: Awareness and perspectives from a representative sample of the US population
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DOI: 10.1002/cncr.31246
Abstract: Although cancer drug shortages are a persistent problem in oncology, little is known about the awareness and perspectives of the US population with respect to shortages. read more here.
Keywords: awareness perspectives; drug shortages; shortages awareness; cancer ... See more keywords
Subcellular-Scale Drug Transport via Ultrasound-Degradable Mesoporous Nanosilicon to Bypass Cancer Drug Resistance.
Sign Up to like & getrecommendations! Published in 2017 at "Small"
DOI: 10.1002/smll.201604228
Abstract: Delivering and releasing anticancer agents directly to their subcellular targets of action in a controlled manner are almost the ultimate goal of pharmacology, but it is challenging. In recent decades, plenty of efforts have been… read more here.
Keywords: drug resistance; subcellular scale; drug; cancer ... See more keywords
Cancer Drug Toxicity: Moving from Patient to Survivor.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer treatment and research"
DOI: 10.1007/978-3-319-43896-2_8
Abstract: Millions of individuals worldwide are living with cancer and have remained disease-free for more than 5 years. These individuals are considered to be cancer survivors. The advent of new targeted therapies and personalized treatment modalities… read more here.
Keywords: toxicity moving; survivorship; cancer; drug toxicity ... See more keywords
Cancer drug resistance induced by EMT: novel therapeutic strategies
Sign Up to like & getrecommendations! Published in 2021 at "Archives of Toxicology"
DOI: 10.1007/s00204-021-03063-7
Abstract: Over the last decade, important clinical benefits have been achieved in cancer patients by using drug-targeting strategies. Nevertheless, drug resistance is still a major problem in most cancer therapies. Epithelial-mesenchymal plasticity (EMP) and tumour microenvironment… read more here.
Keywords: drug resistance; epithelial mesenchymal; resistance; cancer ... See more keywords
Withaferin A: from Ayurvedic folk medicine to preclinical anti-cancer drug.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2019.08.004
Abstract: Despite the recent successes of targeted cancer immuno-therapies, drug resistance and disease relapse remain a huge burden in cancer patient treatment. This has fueled renewed interest in natural product discovery to identify new pharmacophores for… read more here.
Keywords: medicine; folk medicine; pharmacology; cancer ... See more keywords
Functional extracellular vesicles engineered with lipid-grafted hyaluronic acid effectively reverse cancer drug resistance.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2019.119475
Abstract: Multidrug resistance (MDR) is a key issue accounting for ineffectiveness of cancer chemotherapy. Numerous multifunctional nanocarriers have been developed to increase drug delivery efficacy and inhibit drug efflux for overcoming cancer drug resistance. However, limited… read more here.
Keywords: drug; hevs; resistance; cancer ... See more keywords
Application of gelatin nanoconjugates as potential internal stimuli-responsive platforms for cancer drug delivery
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2020.114053
Abstract: Abstract Nanoparticles (NPs) have been continuously utilized for different implementations, most particularly for cancer drug delivery. A large number of NP-based drug delivery systems (DDSs) have been explored for cancer therapy and a variety of… read more here.
Keywords: cancer; drug delivery; stimuli responsive; cancer drug ... See more keywords
Molecular structure, vibrational spectroscopic analysis (IR \& Raman), HOMO-LUMO and NBO analysis of anti-cancer drug sunitinib using DFT method
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2017.07.064
Abstract: Abstract Oxindole and its derivatives have wide applications in different industries such as in synthetic & natural fibers, dyes for hair and plastic materials in addition to their biological importance. In the present study, one… read more here.
Keywords: analysis; vibrational spectroscopic; sunitinib; structure ... See more keywords