Disparities in cancer genetics care by race/ethnicity among pan‐cancer patients with pathogenic germline variants
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DOI: 10.1002/cncr.34434
Abstract: Germline risk assessment is increasing as part of cancer care; however, disparities in subsequent genetic counseling are unknown. read more here.
Keywords: cancer genetics; disparities cancer; genetics care; care race ... See more keywords
Impact of Appointment Waiting Time on Attendance Rates at a Clinical Cancer Genetics Service
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DOI: 10.1007/s10897-018-0259-z
Abstract: The increase in demand for clinical cancer genetics services has impacted the ability to provide services timeously. Given limited resources, this often results in extended appointment waiting times. Over the last 3 years, the Cancer Genetics… read more here.
Keywords: cancer genetics; genetics; waiting times; appointment waiting ... See more keywords
Cancer genetics: A 3D view of genome rearrangements
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DOI: 10.1038/nrg.2017.56
Abstract: Somatic structural genome alterations such as changes in copy number or chromosomal rearrangements can promote genome instability and cancer development, and identification of these mutations is crucial to diagnose cancer early and provide targeted therapies.… read more here.
Keywords: view genome; genetics view; genetics; chromosomal rearrangements ... See more keywords
In vitro functional interrogation of viable circulating tumor associated cells (C-TACs) for evaluating platin resistance
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DOI: 10.1093/annonc/mdz268.099
Abstract: Abstract Background Platins are used extensively to treat Solid Organ Cancers like Ovarian, Breast, Colorectal, Lung, Pancreatic and Bladder Cancer. Eventually however, most cancer patients develop resistance to these treatments. As presently, no assay is… read more here.
Keywords: genetics; genetics limited; resistance; cancer genetics ... See more keywords
Mapping cancer genetics at single-cell resolution
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DOI: 10.1126/scitranslmed.abd3049
Abstract: CRISPR genetic interaction mapping reveals networks of genes that drive cancer phenotypes. CRISPR genetic interaction mapping reveals networks of genes that drive cancer phenotypes. read more here.
Keywords: single cell; genetics; mapping cancer; genetics single ... See more keywords
Consensus for genes to be included on cancer panel tests offered by UK genetics services: guidelines of the UK Cancer Genetics Group
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DOI: 10.1136/jmedgenet-2017-105188
Abstract: Genetic testing for hereditary cancer predisposition has evolved rapidly in recent years with the discovery of new genes, but there is much debate over the clinical utility of testing genes for which there are currently… read more here.
Keywords: genetics; genetics services; cancer; cancer genetics ... See more keywords
The Panorama of Cancer Genetics
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DOI: 10.1158/0008-5472.can-21-0885
Abstract: Cancer, a disease of the genome, is caused by a combination of germline predisposing variants and acquired somatic mutations. A unified view of heritable and acquired genetic factors will improve our understanding of cancer occurrence… read more here.
Keywords: cancer genetics; panorama cancer; genetics; cancer ... See more keywords
A New Frontier for Cancer Genetics: Identification of Germline-Somatic Associations.
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DOI: 10.1158/0008-5472.can-23-0152
Abstract: Studies of the inherited or germline genome have identified rare mutations with large effects and common polymorphisms of more modest effect sizes that are associated with cancer risk. This research has substantially illuminated the etiology… read more here.
Keywords: cancer genetics; new frontier; frontier cancer; germline somatic ... See more keywords
Educational Programme for Cancer Nurses in Genetics, Health Behaviors and Cancer Prevention: A Multidisciplinary Consensus Study
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DOI: 10.3390/jpm12071104
Abstract: (1) Background: Most common hereditary cancers in Europe have been associated with lifestyle behaviors, and people affected are lacking follow up care. However, access to education programmes to increase knowledge on cancer and genetics and… read more here.
Keywords: cancer; cancer nurses; consensus; cancer genetics ... See more keywords