Genomic and clinical characterization of stromal infiltration markers in prostate cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancer"
DOI: 10.1002/cncr.32688
Abstract: The progression of prostate cancer is a complex, multistep process that involves molecular alterations in cells of the tumor and the microenvironment, with associated interactions between the stroma and epithelium. Genomic expression analyses of stromal… read more here.
Keywords: cancer genomic; stromal infiltration; prostate cancer; infiltration markers ... See more keywords
Current progress and issues of cancer genomic medicine in Kyushu University Hospital
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz343.086
Abstract: Abstract Kyushu University Hospital has been designated as a Core Hospital for Cancer Genomic Medicine since February 2018. Our institution promotes cancer genomic medicine collaborating with 16 Cooperative Hospitals for Cancer Genomic Medicine among Kyushu,… read more here.
Keywords: medicine; genomic medicine; kyushu university; cancer genomic ... See more keywords
Understanding the True Prevalence of Prostate Cancer Genomic Subtypes: Use of Inverse Probability Weighting to Correct for Biases in Molecularly Profiled Cohorts.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Urology"
DOI: 10.1097/ju.0000000000001627
Abstract: DISCLAIMER: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our subscribers we are providing this early version of the article. The paper will be… read more here.
Keywords: understanding true; prevalence prostate; prostate cancer; genomic subtypes ... See more keywords
The Japanese Society of Pathology Practical Guidelines on the handling of pathological tissue samples for cancer genomic medicine.
Sign Up to like & getrecommendations! Published in 2021 at "Pathology international"
DOI: 10.1111/pin.13170
Abstract: Clinical cancer genomic testing based on next-generation sequencing can help select genotype-matched therapy and provide diagnostic and prognostic information. Pathological tissue from malignant tumors obtained during routine practice are frequently used for genomic testing. This… read more here.
Keywords: medicine; cancer genomic; pathology; pathological tissue ... See more keywords
C-CAT: The National Datacenter for Cancer Genomic Medicine in Japan
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Discovery"
DOI: 10.1158/2159-8290.cd-22-0417
Abstract: Summary: Since June 2019, under the umbrella of the national health insurance system, Japan has started cancer genomic medicine (CGM) with comprehensive genomic profiling (CGP) tests. The Ministry of Health, Labour and Welfare (MHLW) of… read more here.
Keywords: medicine; genomic medicine; cat national; cancer genomic ... See more keywords
Clinical application of a cancer genomic profiling assay to guide precision medicine decisions
Sign Up to like & getrecommendations! Published in 2017 at "Personalized Medicine"
DOI: 10.2217/pme-2017-0011
Abstract: Aim: Develop and apply a comprehensive and accurate next-generation sequencing based assay to help clinicians to match oncology patients to therapies. Materials & methods: The performance of the CANCERPLEX® assay was assessed using DNA from… read more here.
Keywords: medicine; application cancer; cancer genomic; profiling assay ... See more keywords
Review of prostate cancer genomic studies in Africa
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.911101
Abstract: Prostate cancer (PCa) is the second most commonly diagnosed in men worldwide and one of the most frequent cancers in men in Africa. The heterogeneity of this cancer fosters the need to identify potential genetic… read more here.
Keywords: review prostate; genomic studies; prostate cancer; studies africa ... See more keywords
Analysis of Cancer Genomic Amplifications Identifies Druggable Collateral Dependencies within the Amplicon
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers15061636
Abstract: The identification of novel therapeutic targets for specific cancer molecular subtypes is crucial for the development of precision oncology. In the last years, CRISPR/Cas9 screens have accelerated the discovery and validation of new targets associated… read more here.
Keywords: genomic amplifications; dependencies within; collateral dependencies; cancer genomic ... See more keywords