Using cancer genomics to guide clinical decisions
Sign Up to like & getrecommendations! Published in 2017 at "Cancer"
DOI: 10.1002/cncr.30640
Abstract: Detailed portraits of thousands of cancer genomes are now available, and they illustrate the variety of genomic changes that drive cancer; they are termed landscapes. Cancer landscapes include alterations such as point mutations, indels, rearrangements,… read more here.
Keywords: genomics guide; cancer genomics; using cancer; clinical decisions ... See more keywords
A Primer for Access to Repositories of Cancer-Related Genomic Big Data.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8868-6_1
Abstract: The use of large datasets has become ubiquitous in biomedical sciences. Researchers in the field of cancer genomics have, in recent years, generated large volumes of data from their experiments. Those responsible for production of… read more here.
Keywords: access repositories; cancer genomics; biology; cancer ... See more keywords
Translating cancer genomics into precision medicine with artificial intelligence: applications, challenges and future perspectives
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DOI: 10.1007/s00439-019-01970-5
Abstract: In the field of cancer genomics, the broad availability of genetic information offered by next-generation sequencing technologies and rapid growth in biomedical publication has led to the advent of the big-data era. Integration of artificial… read more here.
Keywords: medicine; precision medicine; cancer genomics; artificial intelligence ... See more keywords
Cervical cancer genomics: an initial step towards personalized approach to therapy
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DOI: 10.1016/j.ebiom.2019.04.025
Abstract: Cervical cancer, well known to be associated human papilloma virus Surgery in early stage cervical cancer is generally curative whereas the (HPV) infection and considered as a preventable cancer byHPV vaccination and organized screening for… read more here.
Keywords: therapy; cancer genomics; cervical cancer; initial step ... See more keywords
Gastric Cancer Genomics: Advances and Future Directions
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2017.01.003
Abstract: Advancement in the field of cancer genomics is revolutionizing the molecular characterization of a wide variety of different cancers. Recent application of large-scale, next-generation sequencing technology to gastric cancer, which remains a major source of… read more here.
Keywords: gastric cancer; cancer genomics; future directions; advances future ... See more keywords
Circulating cell-free DNA: Translating prostate cancer genomics into clinical care.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular aspects of medicine"
DOI: 10.1016/j.mam.2019.100837
Abstract: Only in the past decade tremendous advances have been made in understanding prostate cancer genomics and consequently in applying new treatment strategies. As options regarding treatments are increasing so are the challenges in selecting the… read more here.
Keywords: treatment; cancer genomics; prostate cancer; cell free ... See more keywords
Cancer genomics: Keeping score with immunotherapy response
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Genetics"
DOI: 10.1038/nrg.2017.2
Abstract: the outcome of some cancers, but its potential is limited because only a minority of patients respond to treatment. Thus, a major motivation in the field is to identify ‘signatures’ that might predict with high… read more here.
Keywords: immunotherapy; response; treatment; cancer genomics ... See more keywords
A new era of long-read sequencing for cancer genomics
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Human Genetics"
DOI: 10.1038/s10038-019-0658-5
Abstract: Cancer is a disease largely caused by genomic aberrations. Utilizing many rapidly emerging sequencing technologies, researchers have studied cancer genomes to understand the molecular statuses of cancer cells and to reveal their vulnerabilities, such as… read more here.
Keywords: long read; cancer genomics; new era; era long ... See more keywords
Challenges and solutions to the study of rare childhood tumors.
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DOI: 10.1097/mop.0000000000000857
Abstract: PURPOSE OF REVIEW The majority of progress made in pediatric oncology over the past 50 years has been achieved in the most common cancers. Rare pediatric cancers, which collectively comprise more than 10% of all… read more here.
Keywords: treatment rare; cancer genomics; rare pediatric; study treatment ... See more keywords
Towards Greater Inclusion in Cancer Genomics Studies.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer research"
DOI: 10.1158/0008-5472.can-18-3382
Abstract: The study by Jaratlerdsiri and colleagues represents the first whole-genome sequencing study of prostate cancer from men in sub-Saharan Africa. Preliminary findings include a higher tumor mutation burden in these tumors compared with data from… read more here.
Keywords: inclusion cancer; towards greater; greater inclusion; cancer genomics ... See more keywords
Abstract 5039: Visualization and analysis of cancer genomics data using UCSC Xena
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Research"
DOI: 10.1158/1538-7445.am2022-5039
Abstract: UCSC Xena (http://xena.ucsc.edu/) is a web-based visual integration and exploration tool for multi-omic data and associated clinical and phenotypic annotations. Researchers can easily view and explore public data, their own private data, or both using… read more here.
Keywords: data using; ucsc xena; analysis; xena ... See more keywords