tRNA-derived small RNAs: novel regulators of cancer hallmarks and targets of clinical application
Sign Up to like & getrecommendations! Published in 2021 at "Cell Death Discovery"
DOI: 10.1038/s41420-021-00647-1
Abstract: tRNAs are a group of conventional noncoding RNAs (ncRNAs) with critical roles in the biological synthesis of proteins. Recently, tRNA-derived small RNAs (tsRNAs) were found to have important biological functions in the development of human… read more here.
Keywords: derived small; trna derived; cancer hallmarks; application ... See more keywords
TROVE: a user-friendly tool for visualizing and analyzing cancer hallmarks in signaling networks
Sign Up to like & getrecommendations! Published in 2018 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btx600
Abstract: Summary Cancer hallmarks, a concept that seeks to explain the complexity of cancer initiation and development, provide a new perspective of studying cancer signaling which could lead to a greater understanding of this complex disease.… read more here.
Keywords: signaling networks; cancer hallmarks; trove user; user friendly ... See more keywords
Ion Channels in Cancer: Are Cancer Hallmarks Oncochannelopathies?
Sign Up to like & getrecommendations! Published in 2018 at "Physiological reviews"
DOI: 10.1152/physrev.00044.2016
Abstract: Genomic instability is a primary cause and fundamental feature of human cancer. However, all cancer cell genotypes generally translate into several common pathophysiological features, often referred to as cancer hallmarks. Although nowadays the catalog of… read more here.
Keywords: channels cancer; ion channels; ion channel; cancer hallmarks ... See more keywords
Human Papillomavirus E6 and E7: The Cervical Cancer Hallmarks and Targets for Therapy
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2019.03116
Abstract: Human papillomavirus (HPV)-induced cervical cancer is a major health issue among women from the poorly/under-developed sectors of the world. It accounts for a high-mortality rate because of its late diagnosis and poor prognosis. Initial establishment… read more here.
Keywords: papillomavirus cervical; cervical cancer; cancer hallmarks; human papillomavirus ... See more keywords
Role of the tumor microenvironment in cancer hallmarks and targeted therapy (Review).
Sign Up to like & getrecommendations! Published in 2022 at "International journal of oncology"
DOI: 10.3892/ijo.2022.5471
Abstract: Genetic alterations drive tumor onset and progression. However, the cross‑talk between tumor cells and the benign components of the surrounding stroma can also promote the initiation, progression and metastasis of solid tumors. These cellular and… read more here.
Keywords: review; progression; cancer hallmarks; tumor microenvironment ... See more keywords