Neurologic Toxicities of Cancer Immunotherapies: a Review
Sign Up to like & getrecommendations! Published in 2020 at "Current Neurology and Neuroscience Reports"
DOI: 10.1007/s11910-020-01038-2
Abstract: Purpose of Review This review provides clinical characterization and approach to management of neurotoxicities associated with checkpoint inhibitor therapy and chimeric antigen receptor T cell (CAR T cell) therapy. Recent Findings Immuno-oncology has revolutionized cancer… read more here.
Keywords: therapy; immunotherapies review; neurologic toxicities; cancer ... See more keywords
Cancer immunotherapies repurposed for use in autoimmunity
Sign Up to like & getrecommendations! Published in 2019 at "Nature Biomedical Engineering"
DOI: 10.1038/s41551-019-0359-6
Abstract: Immunotherapies developed to treat cancer can be adapted to treat autoimmunity. read more here.
Keywords: immunotherapies repurposed; use autoimmunity; repurposed use; autoimmunity ... See more keywords
Cancer Immunotherapies Helped Shape COVID Vaccines.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-nd2020-018
Abstract: The record-breaking speed of vaccine development in response to the coronavirus outbreak relied in part on manufacturing infrastructure, technology development, and research tools previously built for oncologic products. read more here.
Keywords: cancer immunotherapies; immunotherapies helped; cancer; helped shape ... See more keywords
Coming of Age: Human Genomics and the Cancer–Immune Set Point
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Immunology Research"
DOI: 10.1158/2326-6066.cir-21-1017
Abstract: Abstract Cancer is largely a disease of the tumor cell genome. As a result, the majority of genetics research in oncology has concentrated on the role of tumor somatic mutations, as well as inherited risk… read more here.
Keywords: human genomics; coming age; cancer immunotherapies; age human ... See more keywords
Cancer Immunotherapies Based on Genetically Engineered Macrophages.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer immunology research"
DOI: 10.1158/2326-6066.cir-22-0030
Abstract: Anticancer immunotherapies are therapeutics aimed at eliciting immune responses against tumor cells. Immunotherapies based on adoptive transfer of engineered immune cells have raised great hopes of cures because of the success of chimeric antigen receptor… read more here.
Keywords: immunotherapies based; cancer immunotherapies; based genetically; tumor ... See more keywords
Nephrotoxicity of Cancer Immunotherapies: Past, Present and Future.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.2018050488
Abstract: Nephrotoxicity from cancer therapies is common and increasingly encountered in clinical practice, such that the subfield of "onco-nephrology" has emerged. Conventional chemotherapeutic drugs and novel agents targeting specific genes/proteins are effective cancer therapies but suffer… read more here.
Keywords: nephrology; immunotherapies past; nephrotoxicity cancer; cancer ... See more keywords
Outcome prediction and evaluation by imaging the key elements of therapeutic responses to cancer immunotherapies using PET.
Sign Up to like & getrecommendations! Published in 2019 at "Current pharmaceutical design"
DOI: 10.2174/1381612825666190829150302
Abstract: Cancer immunotherapy (also known as immuno-oncology), a promising anti-cancer strategy by harnessing the body's own immune system against cancer, has emerged as the "fifth therapeutic pilla" in the field of cancer treatment since surgery, chemotherapy,… read more here.
Keywords: key elements; responses cancer; cancer; cancer immunotherapies ... See more keywords
Manipulation of Glucose Availability to Boost Cancer Immunotherapies
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12102940
Abstract: Simple Summary Substantial effort has been made in recent years to improve the clinical outcome of cancer immunotherapy. Recent findings suggest that manipulation of glucose metabolism can represent a valuable tool to limit cancer cell… read more here.
Keywords: manipulation glucose; cell function; glucose availability; cancer ... See more keywords
Challenges and Opportunities for Effective Cancer Immunotherapies
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12113164
Abstract: Using immunotherapy to treat cancers can be traced back to the 1890s, where a New York physician William Coley used heat-killed bacteria to treat cancer patients, which became known as "Coley's toxin" [...]. read more here.
Keywords: effective cancer; challenges opportunities; opportunities effective; cancer ... See more keywords
Cancer Immunotherapy: Where Next?
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15082358
Abstract: Simple Summary This review highlights the challenges and future directions of cancer immunotherapies. Monoclonal antibody therapies, adaptive immunotherapies, CAR T cells, T cell attracting bispecific antibodies, TCR mimic antibodies, and new targets are reviewed. The… read more here.
Keywords: monoclonal antibody; cancer immunotherapies; cell attracting; cancer ... See more keywords
Advancements in Cancer Immunotherapies
Sign Up to like & getrecommendations! Published in 2022 at "Vaccines"
DOI: 10.3390/vaccines11010059
Abstract: Recent work has suggested involvement of the immune system in biological therapies specifically targeting tumor microenvironment. Substantial advancement in the treatment of malignant tumors utilizing immune cells, most importantly T cells that play a key… read more here.
Keywords: cancer immunotherapies; advancements cancer; cancer;