Harnessing DNA for Immunotherapy: Cancer, Infectious Diseases, and Beyond
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202112273
Abstract: Despite the rapid development of immunotherapy, low response rates, poor therapeutic outcomes, and severe side effects still limit its implementation, making the augmentation of immunotherapy an important goal for current research. DNA, which is principally… read more here.
Keywords: harnessing dna; immunotherapy cancer; cancer infectious; dna ... See more keywords
Nanodelivery of STING agonists against cancer and infectious diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular aspects of medicine"
DOI: 10.1016/j.mam.2021.101007
Abstract: Vaccination is a modality that has been widely explored for the treatment of various diseases. To increase the potency of vaccine formulations, immunostimulatory adjuvants have been regularly exploited, and the stimulator of interferon genes (STING)… read more here.
Keywords: infectious diseases; nanodelivery sting; sting agonists; cancer infectious ... See more keywords
Immunogenic cell death in cancer and infectious disease
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Immunology"
DOI: 10.1038/nri.2016.107
Abstract: Immunogenicity depends on two key factors: antigenicity and adjuvanticity. The presence of exogenous or mutated antigens explains why infected cells and malignant cells can initiate an adaptive immune response provided that the cells also emit… read more here.
Keywords: immunogenic cell; death; cancer infectious; death cancer ... See more keywords
O1-14-2Serial profiling of circulating tumor DNA identifies biomarkers for anti-VEGF chemotherapy in mCRC patients
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Oncology"
DOI: 10.1093/annonc/mdx697.031
Abstract: Satoshi Kaito, Yusuke Kanemasa, Yuki Sasaki, Toshihiro Okuya, Tsukasa Yamaguchi, Miho Tamura, Tatsu Shimoyama, Yashshi Omuro, Tunekazu Hishima, Yoshiharu Maeda Department of Medical Oncology, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan,… read more here.
Keywords: infectious diseases; oncology; tokyo metropolitan; cancer infectious ... See more keywords
Natural DNA Intercalators as Promising Therapeutics for Cancer and Infectious Diseases.
Sign Up to like & getrecommendations! Published in 2019 at "Current cancer drug targets"
DOI: 10.2174/1568009619666191007112516
Abstract: Cancer and infectious diseases are one of the greatest challenges of modern medicine. An unhealthy lifestyle, the improper use of drugs or their abuse are conducive to the increase of morbidity and mortality caused by… read more here.
Keywords: infectious diseases; dna intercalators; natural dna; cancer infectious ... See more keywords
Targeting Proteasomes in Cancer and Infectious Disease: A Parallel Strategy to Treat Malignancies and Microbes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.925804
Abstract: Essential core pathways of cellular biology are preserved throughout evolution, highlighting the importance of these pathways for both bacteria and human cancer cells alike. Cell viability requires a proper balance between protein synthesis and degradation… read more here.
Keywords: cancer infectious; proteasomes cancer; targeting proteasomes; strategy ... See more keywords