Evidence for an Overweight Paradox in Cancer: Insights from Body Composition-Reply to Counterpoint.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer research"
DOI: 10.1158/0008-5472.can-17-3701
Abstract: See Counterpoint by Caan, et al., [p. 1906][1] Dr. Caan and colleagues state that the overweight paradox does in fact exist and that overweight cancer patients have better survival than normal weight cancer patients because… read more here.
Keywords: cancer insights; paradox cancer; insights body; cancer ... See more keywords
Mechanisms of PARP inhibitor resistance in cancer and insights into the DNA damage response
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DOI: 10.1186/s13073-018-0612-8
Abstract: Editorial summaryInhibitors of poly(ADP-ribose) polymerase (PARPi) have entered the clinic for the treatment of patients with cancers that lack homology-directed DNA repair, but drug resistance remains a clinical hurdle. Recent advances in the identification of… read more here.
Keywords: mechanisms parp; parp inhibitor; resistance; resistance cancer ... See more keywords
Ovarian Cancer—Insights into Platinum Resistance and Overcoming It
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DOI: 10.3390/medicina59030544
Abstract: Ovarian cancer is the most lethal gynecologic malignancy. Platinum-based chemotherapy is the backbone of treatment for ovarian cancer, and although the majority of patients initially have a platinum-sensitive disease, through multiple recurrences, they will acquire… read more here.
Keywords: ovarian cancer; resistance platinum; cancer; cancer insights ... See more keywords
Insights into the role of ERp57 in cancer
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DOI: 10.7150/jca.48707
Abstract: Endoplasmic reticulum resident protein 57 (ERp57) has a molecular weight of 57 kDa, belongs to the protein disulfide-isomerase (PDI) family, and is primarily located in the endoplasmic reticulum (ER). ERp57 functions in the quality control… read more here.
Keywords: cancer insights; erp57 cancer; role erp57; erp57 ... See more keywords