Articles with "cancer karyotype" as a keyword



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Reconstructing cancer karyotypes from short read data: the half empty and half full glass

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Published in 2017 at "BMC Bioinformatics"

DOI: 10.1186/s12859-017-1929-9

Abstract: BackgroundDuring cancer progression genomes undergo point mutations as well as larger segmental changes. The latter include, among others, segmental deletions duplications, translocations and inversions.The result is a highly complex, patient-specific cancer karyotype. Using high-throughput technologies… read more here.

Keywords: short read; read data; half; cancer karyotype ... See more keywords