STRring up Cancer with lncRNA.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular cell"
DOI: 10.1016/j.molcel.2018.10.026
Abstract: In this issue of Molecular Cell, Yap et al. (2018) identify a novel lncRNA (PNCTR) that contains short tandem repeats that trap the RNA splicing factor PTBP1 in the perinucleolar compartment and link this sequestration activity… read more here.
Keywords: cancer lncrna; cancer; cell; strring cancer ... See more keywords
Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis
Sign Up to like & getrecommendations! Published in 2020 at "Communications Biology"
DOI: 10.1038/s42003-019-0741-7
Abstract: Long non-coding RNAs (lncRNAs) are a growing focus of cancer genomics studies, creating the need for a resource of lncRNAs with validated cancer roles. Furthermore, it remains debated whether mutated lncRNAs can drive tumorigenesis, and… read more here.
Keywords: tumorigenesis; cancer lncrna; evidence; lncrna census ... See more keywords
Is Evolutionary Conservation a Useful Predictor for Cancer Long Noncoding RNAs? Insights from the Cancer LncRNA Census 3
Sign Up to like & getrecommendations! Published in 2022 at "Non-Coding RNA"
DOI: 10.3390/ncrna8060082
Abstract: Evolutionary conservation is a measure of gene functionality that is widely used to prioritise long noncoding RNAs (lncRNA) in cancer research. Intriguingly, while updating our Cancer LncRNA Census, we observed an inverse relationship between year… read more here.
Keywords: evolutionary conservation; long noncoding; noncoding rnas; cancer lncrna ... See more keywords