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Published in 2019 at "Cancer Research"
DOI: 10.1158/1538-7445.panca19-i22
Abstract: Pancreatic ductal adenocarcinoma (PDA) cells and tumors constitutively activate nutrient scavenging pathways, namely, autophagy (cellular self-catabolism) and macropinocytosis (bulk uptake of extracellular material) in order to maintain metabolic homeostasis. Importantly, both of these pathways converge…
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