Gastric cancer with microsatellite instability displays increased thymidylate synthase expression
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DOI: 10.1002/jso.26822
Abstract: Gastric cancer (GC) with microsatellite instability (MSI) is a less aggressive disease and associated with resistance to 5‐fluorouracil (5‐FU)‐based chemotherapy (CMT). Thymidylate synthase (TS) is inhibited by 5‐FU, and another potential mediator of therapeutic resistance… read more here.
Keywords: cancer microsatellite; microsatellite instability; thymidylate synthase; gastric cancer ... See more keywords