Multifaceted Breast Cancer: The Molecular Connection With Obesity
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.25475
Abstract: Obesity is characterized by a disruption in energy balance regulation that results in an excess accumulation of body fat. Its increasing prevalence poses a major public health concern because it is a risk factor for… read more here.
Keywords: cancer molecular; breast cancer; multifaceted breast; cancer ... See more keywords
Gastric cancer molecular classification and adjuvant therapy: Is there a different benefit according to the subtype?
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.25792
Abstract: Gastric cancer (GC) has been defined in distinct molecular subtypes with different therapeutic implications. However, its clinical significance and prognosis regarding standard chemotherapy (CMT) remains unclear. This study aimed to analyze the impact of perioperative… read more here.
Keywords: molecular classification; gastric cancer; classification adjuvant; cancer ... See more keywords
PD-1 and cancer: molecular mechanisms and polymorphisms
Sign Up to like & getrecommendations! Published in 2017 at "Immunogenetics"
DOI: 10.1007/s00251-017-1015-5
Abstract: The programmed cell death protein 1 (PD-1) is expressed by activated T cells that act as an immunoregulatory molecule, and are responsible for the negative regulation of T cell activation and peripheral tolerance. The PD-1… read more here.
Keywords: molecular mechanisms; cancer; cancer molecular; cell ... See more keywords
Colorectal cancer molecular profiling: from IHC to NGS in search of optimal algorithm
Sign Up to like & getrecommendations! Published in 2017 at "Virchows Archiv"
DOI: 10.1007/s00428-017-2153-8
Abstract: Advances in defining the mutational landscape of colorectal cancer (CRC) over the past decades have revolutionized the molecular understanding and clinical testing algorithms for this disease. Mutation testing is standard of care for the work-up… read more here.
Keywords: colorectal cancer; molecular profiling; profiling ihc; cancer ... See more keywords
Prostate cancer: Molecular imaging and MRI.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of radiology"
DOI: 10.1016/j.ejrad.2021.109893
Abstract: The role of molecular imaging in initial evaluation of men with presumed or established diagnosis of prostate cancer and work up of biochemical recurrence and metastatic disease is rapidly evolving due to superior diagnostic performance… read more here.
Keywords: prostate; prostate cancer; cancer molecular; imaging mri ... See more keywords
Transcription factors in colorectal cancer: molecular mechanism and therapeutic implications
Sign Up to like & getrecommendations! Published in 2020 at "Oncogene"
DOI: 10.1038/s41388-020-01587-3
Abstract: Colorectal cancer (CRC) is a major cause of cancer mortality worldwide, however, the molecular mechanisms underlying the pathogenesis of CRC remain largely unclear. Recent studies have revealed crucial roles of transcription factors in CRC development.… read more here.
Keywords: transcription; factors colorectal; colorectal cancer; cancer molecular ... See more keywords
Molecular Targets of Curcumin and Its Therapeutic Potential for Ovarian Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Nutrition and Cancer"
DOI: 10.1080/01635581.2022.2049321
Abstract: Abstract Ovarian cancer is the fifth most common gynecological cancer in women globally. Conventional chemotherapy is the first therapeutic approach in the treatment of ovarian cancer, but its success is limited by severe side effects,… read more here.
Keywords: ovarian cancer; targets curcumin; cancer molecular; molecular targets ... See more keywords
Noninvasive assessment of breast cancer molecular subtypes on multiparametric MRI using convolutional neural network with transfer learning
Sign Up to like & getrecommendations! Published in 2022 at "Thoracic Cancer"
DOI: 10.1111/1759-7714.14673
Abstract: To evaluate the performances of multiparametric MRI‐based convolutional neural networks (CNNs) for the preoperative assessment of breast cancer molecular subtypes. read more here.
Keywords: assessment breast; cancer molecular; convolutional neural; multiparametric mri ... See more keywords
ClinGen Cancer Somatic Working Group - Standardizing and democratizing access to cancer molecular diagnostic data to drive translational research
Sign Up to like & getrecommendations! Published in 2018 at "Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing"
DOI: 10.1142/9789813235533_0023
Abstract: A growing number of academic and community clinics are conducting genomic testing to inform treatment decisions for cancer patients (1). In the last 3-5 years, there has been a rapid increase in clinical use of… read more here.
Keywords: research; treatment; cancer molecular; cancer ... See more keywords
Research on Cancer Molecular Typing Based on High-Throughput Sequencing Technology
Sign Up to like & getrecommendations! Published in 2021 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2021/9941475
Abstract: This paper studies the role of high-throughput measurement technology in cancer molecular typing. Based on the Dendrix algorithm, the model proposed in this paper selects the gene replication time as an inherent attribute that affects… read more here.
Keywords: gene; model; technology; cancer molecular ... See more keywords
Centrosomal Abnormalities in Pancreatic Cancer: Molecular Mechanisms and Clinical Implications.
Sign Up to like & getrecommendations! Published in 2018 at "Anticancer research"
DOI: 10.21873/anticanres.12345
Abstract: The centrosome is the main microtubule-organizing center in human cells. It regulates normal cell-cycle progression and cell division. Aberrations in the number, structure and function of centrosomes have been found to drive genomic instability and… read more here.
Keywords: pancreatic cancer; centrosomal abnormalities; molecular mechanisms; abnormalities pancreatic ... See more keywords