Perspectives on the past, present, and future of cancer nanomedicine.
Sign Up to like & getrecommendations! Published in 2018 at "Advanced drug delivery reviews"
DOI: 10.1016/j.addr.2018.05.008
Abstract: The justification of cancer nanomedicine relies on enhanced permeation (EP) and retention (R) effect and the capability of intracellular targeting due primarily to size after internalization (endocytosis) into the individual target cells. The EPR effect… read more here.
Keywords: delivery; nanomedicine; cancer nanomedicine; perspectives past ... See more keywords
Exosomes in Cancer Nanomedicine and Immunotherapy: Prospects and Challenges.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in biotechnology"
DOI: 10.1016/j.tibtech.2017.03.004
Abstract: Exosomes (versatile, cell-derived nanovesicles naturally endowed with exquisite target-homing specificity and the ability to surmount in vivo biological barriers) hold substantial promise for developing exciting approaches in drug delivery and cancer immunotherapy. Specifically, bioengineered exosomes… read more here.
Keywords: prospects challenges; nanomedicine immunotherapy; cancer nanomedicine; cancer ... See more keywords
Metallodrugs in cancer nanomedicine.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Society reviews"
DOI: 10.1039/d1cs00468a
Abstract: Metal complexes are extensively used for cancer therapy. The multiple variables available for tuning (metal, ligand, and metal-ligand interaction) offer unique opportunities for drug design, and have led to a vast portfolio of metallodrugs that… read more here.
Keywords: cancer nanomedicine; chemistry; metallodrugs cancer; metal ... See more keywords
One step closer to cancer nanomedicine
Sign Up to like & getrecommendations! Published in 2022 at "Science"
DOI: 10.1126/science.add3666
Abstract: Description High-throughput tool uncovers links between cell signaling and nanomaterial uptake The promise of chemotherapeutic nanomedicine has tantalized clinicians and patients for decades. Nanoparticles (NPs) can directly target tumor cells, which would reduce the amount… read more here.
Keywords: cancer nanomedicine; cell; one step; chemistry ... See more keywords
Cancer nanomedicine developed from total human serum: a novel approach for making personalized nanomedicine.
Sign Up to like & getrecommendations! Published in 2021 at "Nanomedicine"
DOI: 10.2217/nnm-2020-0382
Abstract: Aim: To develop a method for making total serum nanoparticles (TSN) loaded with cytotoxic chemodrugs for cancer therapy. Materials & methods: TSN loaded with paclitaxel (PTX) or piperlongumine (PL) were prepared using high-pressure homogenization and tested… read more here.
Keywords: serum; nanomedicine developed; cancer nanomedicine; cancer ... See more keywords
The EPR effect and beyond: Strategies to improve tumor targeting and cancer nanomedicine treatment efficacy
Sign Up to like & getrecommendations! Published in 2020 at "Theranostics"
DOI: 10.7150/thno.49577
Abstract: Following its discovery more than 30 years ago, the enhanced permeability and retention (EPR) effect has become the guiding principle for cancer nanomedicine development. Over the years, the tumor-targeted drug delivery field has made significant… read more here.
Keywords: cancer; tumor; cancer nanomedicine; epr effect ... See more keywords