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Published in 2020 at "Geburtshilfe und Frauenheilkunde"
DOI: 10.1055/a-1111-8775
Abstract: For patients with locally advanced or metastatic breast cancer, new and effective therapies such as CDK4/6 inhibitors, PARP inhibitors and a PD-L1 inhibitor have been introduced in recent years. This review presents an update on…
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Keywords:
cancer new;
breast;
breast cancer;
cancer 2020 ... See more keywords
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Published in 2022 at "DNA and cell biology"
DOI: 10.1089/dna.2021.1118
Abstract: We present an integrative understanding of cancer as a metabolic multifactorial, multistage disease. We focus on underlying genetics-environmental interactions, evidenced by telomere changes. A range of genetic and epigenetic factors, including physical agents and predisposing…
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Keywords:
new theoretical;
cancer new;
causes cancer;
updated understanding ... See more keywords
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Published in 2021 at "Open Biology"
DOI: 10.1098/rsob.200358
Abstract: Diagnosis and treatment of disease demand a sound understanding of the underlying mechanisms, determining any Achilles' heel that can be targeted in effective therapies. Throughout history, this endeavour to decipher the origin and mechanism of…
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Keywords:
cancer new;
disease;
biology;
cancer ... See more keywords
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Published in 2019 at "Australian and New Zealand Journal of Obstetrics and Gynaecology"
DOI: 10.1111/ajo.13057
Abstract: Incidence of endometrial cancer is increasing rapidly in the developed world and is the most common gynaecological cancer in Australia and New Zealand. In line with obesity rates, the landscape and average age of women…
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Keywords:
cancer new;
new zealand;
status endometrial;
current status ... See more keywords
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Published in 2018 at "ESMO Open"
DOI: 10.1136/esmoopen-2018-000345
Abstract: The nutritional status of every patient with cancer may be negatively affected by the cancer itself (ie, mechanical obstruction) or indirectly through tumour-induced metabolic changes (often referred to as cancer-induced malnutrition or cachexia).1 Most of…
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Keywords:
cancer new;
medical oncologists;
patients cancer;
nutrition patients ... See more keywords
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Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/3744837
Abstract: Applied science nowadays works on the isolation and application of biological macromolecules (BMM). These BMM are isolates from plants using different techniques and used as anticancer, antimicrobial, and anti-inflammatory drugs. Parthenolide (PLT) is one of…
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Keywords:
cancer new;
sesquiterpene lactones;
anti inflammatory;
inflammatory effects ... See more keywords
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Published in 2022 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-21-1059
Abstract: The hallmarks of cancer conceptualization is a heuristic tool for distilling the vast complexity of cancer phenotypes and genotypes into a provisional set of underlying principles. As knowledge of cancer mechanisms has progressed, other facets…
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Keywords:
new dimensions;
biology;
pathology;
cancer ... See more keywords
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Published in 2020 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2020.00516
Abstract: Numerous and different types of cancers possess the dysregulation of the mevalonate pathway as a common feature. Statins, traditionally applied in cardiovascular diseases to reduce lipid levels, subsequently have been discovered to exhibit anti-cancer activities…
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Keywords:
cancer new;
statins cancer;
innovative potential;
potential statins ... See more keywords
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Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.820128
Abstract: Ovarian cancer remains the leading cause of death from gynecological cancer. Survival is significantly related to the stage of the disease at diagnosis. Of quite importance is primary cytoreductive surgery, having as a goal to…
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Keywords:
neoadjuvant treatment;
cancer new;
ovarian cancer;
treatment ovarian ... See more keywords
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Published in 2019 at "Journal of Gynecologic Oncology"
DOI: 10.3802/jgo.2019.30.e46
Abstract: This extensive review summarizes clinical evidence on immunotherapy and targeted therapy currently available for endometrial cancer (EC) and reports the results of the clinical trials and ongoing studies. The research was carried out collecting preclinical…
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Keywords:
cancer new;
new scenarios;
scenarios horizon;
immunotherapy endometrial ... See more keywords