The role of SIRT2 in cancer: A novel therapeutic target
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Cancer"
DOI: 10.1002/ijc.33118
Abstract: Sirtuin 2 (SIRT2) belongs to the sirtuins family. It exists in many tissues and organs of the human body and regulates a wide range of biological functions. Studies have found that the abnormal expression of… read more here.
Keywords: sirt2; role sirt2; cancer novel; sirt2 cancer ... See more keywords
Gastrointestinal cancer: Novel promising first-line combination
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Clinical Oncology"
DOI: 10.1038/nrclinonc.2018.7
Abstract: Changes in serum prostate-specific antigen (PSA) levels, commonly used to evaluate the response of patients with metastatic castration-resistant prostate cancer to treatment, correlate poorly with overall survival. Circulating tumour cell (CTC) counts were explored as… read more here.
Keywords: novel promising; first line; gastrointestinal cancer; cancer novel ... See more keywords
A novel stratification framework for predicting outcome in patients with prostate cancer
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Cancer"
DOI: 10.1038/s41416-020-0799-5
Abstract: Background Unsupervised learning methods, such as Hierarchical Cluster Analysis, are commonly used for the analysis of genomic platform data. Unfortunately, such approaches ignore the well-documented heterogeneous composition of prostate cancer samples. Our aim is to… read more here.
Keywords: cancer; stratification framework; cancer novel; prostate cancer ... See more keywords
Prostate cancer and novel pharmacological treatment options–what’s new for 2022?
Sign Up to like & getrecommendations! Published in 2023 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2023.2181783
Abstract: ABSTRACT Introduction Androgen deprivation therapy (ADT) plus Androgen Receptor Target Agents (ARTAs) or docetaxel are the actual standard of care in prostate cancer (PC). Several therapeutic options are available for pretreated patients: cabazitaxel, olaparib, and… read more here.
Keywords: pharmacological treatment; prostate cancer; prostate; cancer novel ... See more keywords
Molecular staging of gastric cancer with a novel panel of prognostic microRNAs.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.4_suppl.52
Abstract: 52Background: Molecular heterogeneity of gastric cancer discerns patient survival in ways that clinically-based prediction models cannot. To date, individual microRNAs(miRs) expressed by gastric tumors have been associated with survival. We offer a unique molecular-based method… read more here.
Keywords: panel; staging gastric; gastric cancer; cancer novel ... See more keywords
Cervical cancer and novel therapeutic and diagnostic approaches using chitosan as a carrier: A review.
Sign Up to like & getrecommendations! Published in 2022 at "Current pharmaceutical design"
DOI: 10.2174/1381612828666220512101538
Abstract: In our knowledge, using appropriate carriers in delivery of chemotherapeutic drugs, would result in better targeting and therefore it would increase the effectiveness and decrease the side effects of drugs. Chitosan, a natural polymer derived… read more here.
Keywords: cervical cancer; novel therapeutic; therapeutic diagnostic; cancer novel ... See more keywords
Vitamin D in liver cancer: novel insights and future perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Croatian Medical Journal"
DOI: 10.3325/cmj.2022.63.187
Abstract: Vitamin D has been a focus of attention in liver cancer due to its direct and indirect antineoplastic effects. This review critically evaluates data from recently published basic and clinical studies investigating the role of… read more here.
Keywords: vitamin liver; liver cancer; cancer novel; cancer ... See more keywords
Yeast-Derived β-Glucan in Cancer: Novel Uses of a Traditional Therapeutic
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20153618
Abstract: An increased understanding of the complex mechanisms at play within the tumor microenvironment (TME) has emphasized the need for the development of strategies that target immune cells within the TME. Therapeutics that render the TME… read more here.
Keywords: yeast derived; derived glucan; cancer novel; novel uses ... See more keywords