Establishment of 2.5D organoid culture model using 3D bladder cancer organoid culture
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-66229-w
Abstract: Three-dimensional (3D) organoid culture holds great promises in cancer precision medicine. However, Matrigel and stem cell-stimulating supplements are necessary for culturing 3D organoid cells. It costs a lot of money and consumes more time and effort… read more here.
Keywords: organoid culture; culture; bladder cancer; cancer organoid ... See more keywords
Human gastric cancer modelling using organoids
Sign Up to like & getrecommendations! Published in 2019 at "Gut"
DOI: 10.1136/gutjnl-2017-314549
Abstract: Objective Gastric cancer is the second leading cause of cancer-related deaths and the fifth most common malignancy worldwide. In this study, human and mouse gastric cancer organoids were generated to model the disease and perform… read more here.
Keywords: mouse gastric; gastric cancer; cancer organoid; cancer organoids ... See more keywords
Cancer organoid co-culture model system: Novel approach to guide precision medicine
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1061388
Abstract: Three-dimensional cancer organoids derived from self-organizing cancer stems are ex vivo miniatures of tumors that faithfully recapitulate their structure, distinctive cancer features, and genetic signatures. As novel tools, current cancer organoids have been well established… read more here.
Keywords: cancer organoids; organoid culture; medicine; cancer ... See more keywords
Cancer organoid applications to investigate chemotherapy resistance
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.1067207
Abstract: In clinical practice, a large proportion of cancer patients receive chemotherapy, yet tumors persist or acquire resistance; removing this obstacle could help to lower the number of cancer-related fatalities. All areas of cancer research are… read more here.
Keywords: organoid applications; resistance; chemotherapy; drug ... See more keywords
Modeling Pancreatic Cancer with Patient-Derived Organoids Integrating Cancer-Associated Fibroblasts
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DOI: 10.3390/cancers14092077
Abstract: Simple Summary Pancreatic cancer tissue is resistant to anticancer drugs because of its complex microenvironment. Cancer-associated fibroblasts (CAFs) are an important source of extracellular matrix components, which alter the physical and chemical properties of pancreatic… read more here.
Keywords: pancreatic cancer; associated fibroblasts; model; cancer associated ... See more keywords